Disability-Adjusted Life Years for Breast and Reproductive System Cancers in Cuban Women of Childbearing Age

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Autore principale: Emma Domínguez
Natura: Artículo científico
Lingua:en
Pubblicazione: Medical Education Cooperation with Cuba 2014
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author Emma Domínguez
author_facet Emma Domínguez
contents Disability-Adjusted Life Years for Breast and Reproductive System Cancers in Cuban Women of Childbearing Age Emma Domínguez Felipe Santana Armando H. Seuc Yaima Galán Medicina Cuba cancer breast fertility Disability INTRODUCTION Disability-adjusted life years is a composite mea- sure that integrates the components of mortality and morbidity. It is a useful indicator of overall disease burden and is particularly useful for evaluating health intervention outcomes. In the cases of breast and reproductive system cancers, these can also negatively affect child- bearing opportunities for young women. OBJECTIVE Determine disability-adjusted life years for breast and reproductive system cancers in Cuban women aged 15–44 years dur- ing the period 1990–2006. METHODS A national epidemiological study was conducted using Cuba’s disease and vital statistics registry data for 1990, 1995, 2000 and 2006. Disability-adjusted life years in women aged 15–44 years were calculated for breast cancer and three female reproductive sys- tem cancers (cervical, endometrial and ovarian), by summing years of life lost due to premature mortality and years lived with disability. Years of life lost due to premature mortality were determined based RQDJHVSHFL¿FHVWLPDWHVRIOLIHH[SHFWDQF\<HDUVOLYHGZLWKG LVDELOLW\ were calculated as the product of severities (provided by the 1990 Global Burden of Disease study) and incidence and average dura- tion, both obtained via the DISMOD II program. Data entered in the program include national statistics on incidence, prevalence, and mor- tality. RESULTS Breast cancer and cervical cancer proved to have the high- est rates of potential years of life lost due to premature mortality, with the sharpest increases in the period (from 139 to 206.5 and 114.7 to 215.2 per 100,000, respectively). Endometrial and ovarian neoplasms crept up more slowly. An increase in years lived with disability was seen in three of these four types of cancer; only cervical cancer saw a decline (from 12.7 to 9 per 100,000). Breast cancer and cervical cancer presented the highest levels of disability-adjusted life years for all four years studied, rising from 146.9 to 227.8 and 127.4 to 224.2 per 100,000, respectively between 1990 and 2006. CONCLUSIONS An unfavorable trend in disability-adjusted life years was seen for breast and cervical cancer between 1990 and 2006 in Cuban women of childbearing age. 2014 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437542098003 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.3-4 Vol.16
format Artículo científico
id redalyc_437542098003
institution Redalyc
language en
publishDate 2014
publisher Medical Education Cooperation with Cuba
spellingShingle Disability-Adjusted Life Years for Breast and Reproductive System Cancers in Cuban Women of Childbearing Age
Emma Domínguez
Medicina
Cuba
cancer
breast
fertility
Disability
Disability-Adjusted Life Years for Breast and Reproductive System Cancers in Cuban Women of Childbearing Age Emma Domínguez Felipe Santana Armando H. Seuc Yaima Galán Medicina Cuba cancer breast fertility Disability INTRODUCTION Disability-adjusted life years is a composite mea- sure that integrates the components of mortality and morbidity. It is a useful indicator of overall disease burden and is particularly useful for evaluating health intervention outcomes. In the cases of breast and reproductive system cancers, these can also negatively affect child- bearing opportunities for young women. OBJECTIVE Determine disability-adjusted life years for breast and reproductive system cancers in Cuban women aged 15–44 years dur- ing the period 1990–2006. METHODS A national epidemiological study was conducted using Cuba’s disease and vital statistics registry data for 1990, 1995, 2000 and 2006. Disability-adjusted life years in women aged 15–44 years were calculated for breast cancer and three female reproductive sys- tem cancers (cervical, endometrial and ovarian), by summing years of life lost due to premature mortality and years lived with disability. Years of life lost due to premature mortality were determined based RQDJHVSHFL¿FHVWLPDWHVRIOLIHH[SHFWDQF\<HDUVOLYHGZLWKG LVDELOLW\ were calculated as the product of severities (provided by the 1990 Global Burden of Disease study) and incidence and average dura- tion, both obtained via the DISMOD II program. Data entered in the program include national statistics on incidence, prevalence, and mor- tality. RESULTS Breast cancer and cervical cancer proved to have the high- est rates of potential years of life lost due to premature mortality, with the sharpest increases in the period (from 139 to 206.5 and 114.7 to 215.2 per 100,000, respectively). Endometrial and ovarian neoplasms crept up more slowly. An increase in years lived with disability was seen in three of these four types of cancer; only cervical cancer saw a decline (from 12.7 to 9 per 100,000). Breast cancer and cervical cancer presented the highest levels of disability-adjusted life years for all four years studied, rising from 146.9 to 227.8 and 127.4 to 224.2 per 100,000, respectively between 1990 and 2006. CONCLUSIONS An unfavorable trend in disability-adjusted life years was seen for breast and cervical cancer between 1990 and 2006 in Cuban women of childbearing age. 2014 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437542098003 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.3-4 Vol.16
title Disability-Adjusted Life Years for Breast and Reproductive System Cancers in Cuban Women of Childbearing Age
topic Medicina
Cuba
cancer
breast
fertility
Disability
url https://www.redalyc.org/articulo.oa?id=437542098003