Neonatal Surgery Case Fatality and Associated Factors in a Cuban Pediatric Hospital, 2005–2015

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Autore principale: Regla C. Broche-Candó
Natura: Artículo científico
Lingua:en
Pubblicazione: Medical Education Cooperation with Cuba 2017
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_version_ 1876432092335702016
author Regla C. Broche-Candó
author_facet Regla C. Broche-Candó
contents Neonatal Surgery Case Fatality and Associated Factors in a Cuban Pediatric Hospital, 2005–2015 Regla C. Broche-Candó Oramis Sosa-Palacios Eduardo Morales-Mesa Mirtha Pla-Ampudia Oneida Reyes-Romero María Antonia Pérez-Moré Medicina Cuba surgery neonatal mortality case fatality INTRODUCTION Newborns in need of surgery are a challenge to manage and require highly specialized centers with multidisciplinary surgical teams. Since the 1980s, neonatal surgical survival has increased by up to 70% in some countries, mainly due to advances in neonatal intensive care, anesthesia and surgical technique. OBJECTIVE Describe surgical case fatality and survival in a neonatal reference hospital in Cuba, estimate risk of death, and identify potential risk predictors among neonatal characteristics. METHODS A retrospective cohort study was conducted based on hospital administrative data and clinical records for a series of surgical cases in the neonatal intensive care unit of Havanas William Soler University Childrens Hospital from January 2005 to December 2015. All neonates who underwent surgery during the study period were included. The dependent variable was discharge status (alive, deceased); independent variables were: sex, age (in days) at time of surgery, gestational age, birth weight, indication for surgery, surgical order ( Þ rst, repeat), and presence of sepsis or other postoperative complications. The study used contingency tables to analyze associations between neonatal characteristics and discharge status. A classi Þ cation tree was used to obtain simple estimates of surgical risk. RESULTS Survival was 91.3% (675/739) among 739 neonates who underwent surgery. The majority were male (58.7%, 434/739), full term (84.2%, 622/739), and of normal birth weight (80.6%, 596/739). Most surgeries were performed in the Þ rst 10 days of life. Digestive system anomalies constituted the most common surgical indication (57.6%, 426/739); among these anorectal malformations (26.8%, 114/426) and esophageal atresia (17.4%, 74/426) predominated. Survival rates were lower for digestive perforation (57.7%, 15/26), gastroschisis (57.1%, 4/7) and intestinal atresia (73%, 27/37). Neonates in the youngest and oldest age groups at time of surgery faced highest risk of death, especially those in the older group. Term infants with normal birth weight operated on for the Þ rst time had survival rates >95%. CONCLUSIONS Survival was high and low birth weight conferred the worst prognosis. Infants with normal birth weight operated on for the Þ rst time had the greatest probability of survival. 2017 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437552190004 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.2-3 Vol.19
format Artículo científico
id redalyc_437552190004
institution Redalyc
language en
publishDate 2017
publisher Medical Education Cooperation with Cuba
spellingShingle Neonatal Surgery Case Fatality and Associated Factors in a Cuban Pediatric Hospital, 2005–2015
Regla C. Broche-Candó
Medicina
Cuba
surgery
neonatal
mortality
case fatality
Neonatal Surgery Case Fatality and Associated Factors in a Cuban Pediatric Hospital, 2005–2015 Regla C. Broche-Candó Oramis Sosa-Palacios Eduardo Morales-Mesa Mirtha Pla-Ampudia Oneida Reyes-Romero María Antonia Pérez-Moré Medicina Cuba surgery neonatal mortality case fatality INTRODUCTION Newborns in need of surgery are a challenge to manage and require highly specialized centers with multidisciplinary surgical teams. Since the 1980s, neonatal surgical survival has increased by up to 70% in some countries, mainly due to advances in neonatal intensive care, anesthesia and surgical technique. OBJECTIVE Describe surgical case fatality and survival in a neonatal reference hospital in Cuba, estimate risk of death, and identify potential risk predictors among neonatal characteristics. METHODS A retrospective cohort study was conducted based on hospital administrative data and clinical records for a series of surgical cases in the neonatal intensive care unit of Havanas William Soler University Childrens Hospital from January 2005 to December 2015. All neonates who underwent surgery during the study period were included. The dependent variable was discharge status (alive, deceased); independent variables were: sex, age (in days) at time of surgery, gestational age, birth weight, indication for surgery, surgical order ( Þ rst, repeat), and presence of sepsis or other postoperative complications. The study used contingency tables to analyze associations between neonatal characteristics and discharge status. A classi Þ cation tree was used to obtain simple estimates of surgical risk. RESULTS Survival was 91.3% (675/739) among 739 neonates who underwent surgery. The majority were male (58.7%, 434/739), full term (84.2%, 622/739), and of normal birth weight (80.6%, 596/739). Most surgeries were performed in the Þ rst 10 days of life. Digestive system anomalies constituted the most common surgical indication (57.6%, 426/739); among these anorectal malformations (26.8%, 114/426) and esophageal atresia (17.4%, 74/426) predominated. Survival rates were lower for digestive perforation (57.7%, 15/26), gastroschisis (57.1%, 4/7) and intestinal atresia (73%, 27/37). Neonates in the youngest and oldest age groups at time of surgery faced highest risk of death, especially those in the older group. Term infants with normal birth weight operated on for the Þ rst time had survival rates >95%. CONCLUSIONS Survival was high and low birth weight conferred the worst prognosis. Infants with normal birth weight operated on for the Þ rst time had the greatest probability of survival. 2017 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437552190004 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.2-3 Vol.19
title Neonatal Surgery Case Fatality and Associated Factors in a Cuban Pediatric Hospital, 2005–2015
topic Medicina
Cuba
surgery
neonatal
mortality
case fatality
url https://www.redalyc.org/articulo.oa?id=437552190004