Thrombotic Microangiopathy in Patients Recovering from COVID-19
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| Format: | Artículo científico |
| Sprache: | en |
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Medical Education Cooperation with Cuba
2022
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| _version_ | 1876448956149399552 |
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| author | Laura López-Marín |
| author_facet | Laura López-Marín |
| contents | Thrombotic Microangiopathy in Patients Recovering from COVID-19 Laura López-Marín Raymed A. Bacallao-Méndez Betsy Llerena-Ferrer Aymara Badell-Moore Yamile García-Villar Leticia Rodríguez-Leyva Raúl Herrera-Valdés Medicina 19 Cuba COVID kidney biopsy INTRODUCTION During the pandemic caused by the SARS-CoV-2 virus, some patients who develop severe forms of COVID-19 present thrombotic microangiopathy in the course of the disease’s clinical progression.METHODS Data came from direct patient observation and clinical records. We performed a kidney biopsy and used optical microscopy and immunofluorescence techniques.RESULTS We present the case of a 78-year-old male patient, mestizo, overweight with a history of high blood pressure, ischemic cardiopathy and chronic obstructive pulmonary disease who was first admitted to the hospital due to respiratory symptoms and diarrhea related to COVID-19, from which he recovered. He was subsequently readmitted with symptoms of acute renal dysfunction accompanied by mild anemia and thrombocytopenia; at the same time, he resulted negative for COVID-19 via a real-time polymerase chain reaction test. A kidney biopsy revealed thrombi in glomerular capillaries, acute tubular necrosis, thickening of extraglomerular blood vessel walls, and C3 deposits in the glomerular tufts.CONCLUSIONS We describe a case of thrombotic microangiopathy with kidney biopsy in a patient recovering from COVID-19. Acute renal dysfunction is a form of thrombotic microangiopathy that has been observed in patients recovering from COVID-19. 2022 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437569929007 https://www.redalyc.org/journal/4375/437569929007/ https://www.redalyc.org/journal/4375/437569929007/html/ https://www.redalyc.org/journal/4375/437569929007/437569929007.epub https://www.redalyc.org/journal/4375/437569929007/movil https://doi.org/10.37757/MR2022.V24.N1.2 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.1 Vol.24 |
| format | Artículo científico |
| id | redalyc_437569929007 |
| institution | Redalyc |
| language | en |
| publishDate | 2022 |
| publisher | Medical Education Cooperation with Cuba |
| spellingShingle | Thrombotic Microangiopathy in Patients Recovering from COVID-19 Laura López-Marín Medicina 19 Cuba COVID kidney biopsy Thrombotic Microangiopathy in Patients Recovering from COVID-19 Laura López-Marín Raymed A. Bacallao-Méndez Betsy Llerena-Ferrer Aymara Badell-Moore Yamile García-Villar Leticia Rodríguez-Leyva Raúl Herrera-Valdés Medicina 19 Cuba COVID kidney biopsy INTRODUCTION During the pandemic caused by the SARS-CoV-2 virus, some patients who develop severe forms of COVID-19 present thrombotic microangiopathy in the course of the disease’s clinical progression.METHODS Data came from direct patient observation and clinical records. We performed a kidney biopsy and used optical microscopy and immunofluorescence techniques.RESULTS We present the case of a 78-year-old male patient, mestizo, overweight with a history of high blood pressure, ischemic cardiopathy and chronic obstructive pulmonary disease who was first admitted to the hospital due to respiratory symptoms and diarrhea related to COVID-19, from which he recovered. He was subsequently readmitted with symptoms of acute renal dysfunction accompanied by mild anemia and thrombocytopenia; at the same time, he resulted negative for COVID-19 via a real-time polymerase chain reaction test. A kidney biopsy revealed thrombi in glomerular capillaries, acute tubular necrosis, thickening of extraglomerular blood vessel walls, and C3 deposits in the glomerular tufts.CONCLUSIONS We describe a case of thrombotic microangiopathy with kidney biopsy in a patient recovering from COVID-19. Acute renal dysfunction is a form of thrombotic microangiopathy that has been observed in patients recovering from COVID-19. 2022 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437569929007 https://www.redalyc.org/journal/4375/437569929007/ https://www.redalyc.org/journal/4375/437569929007/html/ https://www.redalyc.org/journal/4375/437569929007/437569929007.epub https://www.redalyc.org/journal/4375/437569929007/movil https://doi.org/10.37757/MR2022.V24.N1.2 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.1 Vol.24 |
| title | Thrombotic Microangiopathy in Patients Recovering from COVID-19 |
| topic | Medicina 19 Cuba COVID kidney biopsy |
| url | https://www.redalyc.org/articulo.oa?id=437569929007 https://www.redalyc.org/journal/4375/437569929007/ https://www.redalyc.org/journal/4375/437569929007/html/ https://www.redalyc.org/journal/4375/437569929007/437569929007.epub https://www.redalyc.org/journal/4375/437569929007/movil https://doi.org/10.37757/MR2022.V24.N1.2 |