Brain Metastases in Havana Cancer Patients
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| Format: | Artículo científico |
| Language: | en |
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Medical Education Cooperation with Cuba
2018
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| _version_ | 1876480982882713600 |
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| author | Joel Caballero-García |
| author_facet | Joel Caballero-García |
| contents | Brain Metastases in Havana Cancer Patients Joel Caballero-García Rosainerys Jiménez-Martínez Adolfo M. Giol-Álvarez Mario de Jesús Caso-Cantero Orlando Cruz-García Diana de los Ángeles García-López Medicina Cuba brain Cancer prevalence epidemiology INTRODUCTION Cancer is a major public health problem worldwide and in Cuba. Approximately one third of cancer patients develop a brain metastasis. Despite this, epidemiological studies are scarce, internationally and in Cuba; published research is mainly limited to autopsy studies and hospital case series. OBJECTIVE Characterize patients with brain metastases residing in Habana del Este Municipality, Havana, Cuba, with respect to demographics, metastasis location and primary tumor site. METHODS A retrospective descriptive study was carried out with data for all patients with histologically confi rmed cancer diagnosed in 2014 and registered in primary health care in Habana del Este Municipality. Diagnostic reports from computed tomography and/or magnetic resonance imaging were used to identify patients with brain metastases. Study variables were age, sex, skin color, number and location of brain metastases, control of primary tumor, and presence of extracranial metastases. Percentages were calculated and presented in tables. RESULTS We identifi ed 832 cancer patients in the Habana del Este population of 181,473 (prevalence 458.5 per 100,000 population). Among patients with cancer, 27.6% (230/832) had brain tumors, among which 83% (191/230) were brain metastases and 17% (39/230) primary tumors, a ratio of 4.9:1. Brain metastases appeared in 23% (191/832) of cancer patients (prevalence 105.2 per 100,000 population). Among patients with brain metastases, 48.2% (92/191) were aged 41–60 years and 61.3% (117/191) were female sex. The majority, 59.7% (114/191) had multiple metastases. The most frequent primary tumor location was the breast (40.8%, 78/191), followed by the lung (31.9%; 61/191); 46.8% (211/451) of brain metastases were in the parietal lobe. CONCLUSIONS Brain metastases are more prevalent in this Cuban municipality than reported in other countries, but they constitute a higher proportion of cancer cases than seen in other population-based studies. The study’s results underline the importance of detecting brain metastasis early, to permit timely interventions to improve quality of life and survival. 2018 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437577133003 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.1 Vol.20 |
| format | Artículo científico |
| id | redalyc_437577133003 |
| institution | Redalyc |
| language | en |
| publishDate | 2018 |
| publisher | Medical Education Cooperation with Cuba |
| spellingShingle | Brain Metastases in Havana Cancer Patients Joel Caballero-García Medicina Cuba brain Cancer prevalence epidemiology Brain Metastases in Havana Cancer Patients Joel Caballero-García Rosainerys Jiménez-Martínez Adolfo M. Giol-Álvarez Mario de Jesús Caso-Cantero Orlando Cruz-García Diana de los Ángeles García-López Medicina Cuba brain Cancer prevalence epidemiology INTRODUCTION Cancer is a major public health problem worldwide and in Cuba. Approximately one third of cancer patients develop a brain metastasis. Despite this, epidemiological studies are scarce, internationally and in Cuba; published research is mainly limited to autopsy studies and hospital case series. OBJECTIVE Characterize patients with brain metastases residing in Habana del Este Municipality, Havana, Cuba, with respect to demographics, metastasis location and primary tumor site. METHODS A retrospective descriptive study was carried out with data for all patients with histologically confi rmed cancer diagnosed in 2014 and registered in primary health care in Habana del Este Municipality. Diagnostic reports from computed tomography and/or magnetic resonance imaging were used to identify patients with brain metastases. Study variables were age, sex, skin color, number and location of brain metastases, control of primary tumor, and presence of extracranial metastases. Percentages were calculated and presented in tables. RESULTS We identifi ed 832 cancer patients in the Habana del Este population of 181,473 (prevalence 458.5 per 100,000 population). Among patients with cancer, 27.6% (230/832) had brain tumors, among which 83% (191/230) were brain metastases and 17% (39/230) primary tumors, a ratio of 4.9:1. Brain metastases appeared in 23% (191/832) of cancer patients (prevalence 105.2 per 100,000 population). Among patients with brain metastases, 48.2% (92/191) were aged 41–60 years and 61.3% (117/191) were female sex. The majority, 59.7% (114/191) had multiple metastases. The most frequent primary tumor location was the breast (40.8%, 78/191), followed by the lung (31.9%; 61/191); 46.8% (211/451) of brain metastases were in the parietal lobe. CONCLUSIONS Brain metastases are more prevalent in this Cuban municipality than reported in other countries, but they constitute a higher proportion of cancer cases than seen in other population-based studies. The study’s results underline the importance of detecting brain metastasis early, to permit timely interventions to improve quality of life and survival. 2018 artículo científico 1555-7960 https://www.redalyc.org/articulo.oa?id=437577133003 en http://www.redalyc.org/revista.oa?id=4375 MEDICC Review application/pdf Medical Education Cooperation with Cuba MEDICC Review (Estados Unidos de América) Num.1 Vol.20 |
| title | Brain Metastases in Havana Cancer Patients |
| topic | Medicina Cuba brain Cancer prevalence epidemiology |
| url | https://www.redalyc.org/articulo.oa?id=437577133003 |