Dexmedetomidine in spinal anesthesia for cesarean section
Fuente:
Redalyc
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Format: | Artículo científico |
| Sprache: | en |
| Veröffentlicht: |
Universidad Mayor de San Simón
2020
|
| Schlagworte: | |
| Online-Zugang: | |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| _version_ | 1876458114786525184 |
|---|---|
| author | Patricia Alegre Andrade |
| author_facet | Patricia Alegre Andrade |
| contents | Dexmedetomidine in spinal anesthesia for cesarean section Patricia Alegre Andrade Medicina Dexmedetomidine caesarean section spinal anesthesia Dexmedetomidine is an ?-agonist, widely used and popular worldwide, but little is known about its intrathecal use in Bolivian population, especially in obstetric patients. Objectives: to evaluate the effect of intrathecal dexmedetomidine in obstetric anesthesia and observe side effects of the drug. Methods: randomized, single-blinded clinical trial. The sample was 123 patients, each group of 41 patients fulfilling both criteria. Group B (bupivacaine + fentanyl); group D2 (bupivacaine + fentanyl+ dexmedetomidine 2 µg) and group B3 (bupivacaine + fentanyl+ dexmedetomidine 3 µg). Statistical analysis: SPSS® 25 and Excel® 2016 software were used. With a confidence level of 95% and a sampling error of 13%. Results: motor block duration was 106.5 ± 16 minutes in group B; 142.3 ± 28.2 minutes in group D2 and 145.6 ± 16.7 minutes in group D3. Being significant between the study groups (p-value < 0.000). PAM with statistical significance before and after birth. Heart rate significant at 15, 30 and 45 minutes (p-value < 0.000, 0.001, 0.004, 0.000 and 0.002). Etilefrin in group B was 3.44 ± 1.8 ml; for group D3 it was 1.8 ± 2.7 ml and group D2 it was 0.85 ± 1.6 ml. Conclusions: better hemodynamic stability with 2 µg dexmedetomidine, lower incidence of hypotension, use of vasopressors, few complications and an excellent state of maternal sedation. 2020 artículo científico 1012-2966 https://www.redalyc.org/articulo.oa?id=445674705016 https://www.redalyc.org/journal/4456/445674705016/ https://www.redalyc.org/journal/4456/445674705016/html/ https://www.redalyc.org/journal/4456/445674705016/445674705016.epub https://www.redalyc.org/journal/4456/445674705016/movil en http://www.redalyc.org/revista.oa?id=4456 Gaceta Médica Boliviana application/pdf Universidad Mayor de San Simón Gaceta Médica Boliviana (Estado Plurinacional de Bolivia) Num.2 Vol.43 |
| format | Artículo científico |
| id | redalyc_445674705016 |
| institution | Redalyc |
| language | en |
| publishDate | 2020 |
| publisher | Universidad Mayor de San Simón |
| spellingShingle | Dexmedetomidine in spinal anesthesia for cesarean section Patricia Alegre Andrade Medicina Dexmedetomidine caesarean section spinal anesthesia Dexmedetomidine in spinal anesthesia for cesarean section Patricia Alegre Andrade Medicina Dexmedetomidine caesarean section spinal anesthesia Dexmedetomidine is an ?-agonist, widely used and popular worldwide, but little is known about its intrathecal use in Bolivian population, especially in obstetric patients. Objectives: to evaluate the effect of intrathecal dexmedetomidine in obstetric anesthesia and observe side effects of the drug. Methods: randomized, single-blinded clinical trial. The sample was 123 patients, each group of 41 patients fulfilling both criteria. Group B (bupivacaine + fentanyl); group D2 (bupivacaine + fentanyl+ dexmedetomidine 2 µg) and group B3 (bupivacaine + fentanyl+ dexmedetomidine 3 µg). Statistical analysis: SPSS® 25 and Excel® 2016 software were used. With a confidence level of 95% and a sampling error of 13%. Results: motor block duration was 106.5 ± 16 minutes in group B; 142.3 ± 28.2 minutes in group D2 and 145.6 ± 16.7 minutes in group D3. Being significant between the study groups (p-value < 0.000). PAM with statistical significance before and after birth. Heart rate significant at 15, 30 and 45 minutes (p-value < 0.000, 0.001, 0.004, 0.000 and 0.002). Etilefrin in group B was 3.44 ± 1.8 ml; for group D3 it was 1.8 ± 2.7 ml and group D2 it was 0.85 ± 1.6 ml. Conclusions: better hemodynamic stability with 2 µg dexmedetomidine, lower incidence of hypotension, use of vasopressors, few complications and an excellent state of maternal sedation. 2020 artículo científico 1012-2966 https://www.redalyc.org/articulo.oa?id=445674705016 https://www.redalyc.org/journal/4456/445674705016/ https://www.redalyc.org/journal/4456/445674705016/html/ https://www.redalyc.org/journal/4456/445674705016/445674705016.epub https://www.redalyc.org/journal/4456/445674705016/movil en http://www.redalyc.org/revista.oa?id=4456 Gaceta Médica Boliviana application/pdf Universidad Mayor de San Simón Gaceta Médica Boliviana (Estado Plurinacional de Bolivia) Num.2 Vol.43 |
| title | Dexmedetomidine in spinal anesthesia for cesarean section |
| topic | Medicina Dexmedetomidine caesarean section spinal anesthesia |
| url | https://www.redalyc.org/articulo.oa?id=445674705016 https://www.redalyc.org/journal/4456/445674705016/ https://www.redalyc.org/journal/4456/445674705016/html/ https://www.redalyc.org/journal/4456/445674705016/445674705016.epub https://www.redalyc.org/journal/4456/445674705016/movil |