In vitro multiplication of Toxoplasma gondii and Trypanosoma cruzi in mouse, rat, and hamster astrocytes
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| Format: | Artículo científico |
| Sprache: | en |
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Universidad de Costa Rica
2003
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| _version_ | 1876462444296011776 |
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| author | Adriana Troyo |
| author_facet | Adriana Troyo |
| contents | In vitro multiplication of Toxoplasma gondii and Trypanosoma cruzi in mouse, rat, and hamster astrocytes Adriana Troyo Misael Chinchilla Biología rat mouse hamster astrocyte cell culture The infection and multiplication of Toxoplasma gondii and Trypanosoma cruzi were compared in primary cultures of white rat, mouse and hamster astrocytes. These cells were cultured on cover slides and infected with T. gondii tachyzoites or T. cruzi blood trypomastigotes. Results show that hamster astrocytes are more susceptible to the multiplication of both parasites than rat and mouse cells. There was no statistical difference between the T. gondii infection in rat and mouse astrocytes (p<0.05), and this suggests an important role of other mechanisms or cells in the white rat natural resistance to this parasite. Because the hamster astrocytes are less resistant to these parasites multiplication and not necessarily to the invasion, any difference observed could be due to an intracellular effect: hamster brain astrocytes favor survival and multiplication of these parasites. 2003 artículo científico 0034-7744 https://www.redalyc.org/articulo.oa?id=44911882005 en http://www.redalyc.org/revista.oa?id=449 Revista de Biología Tropical application/pdf Universidad de Costa Rica Revista de Biología Tropical (Costa Rica) Num.3-4 Vol.51 |
| format | Artículo científico |
| id | redalyc_44911882005 |
| institution | Redalyc |
| language | en |
| publishDate | 2003 |
| publisher | Universidad de Costa Rica |
| spellingShingle | In vitro multiplication of Toxoplasma gondii and Trypanosoma cruzi in mouse, rat, and hamster astrocytes Adriana Troyo Biología rat mouse hamster astrocyte cell culture In vitro multiplication of Toxoplasma gondii and Trypanosoma cruzi in mouse, rat, and hamster astrocytes Adriana Troyo Misael Chinchilla Biología rat mouse hamster astrocyte cell culture The infection and multiplication of Toxoplasma gondii and Trypanosoma cruzi were compared in primary cultures of white rat, mouse and hamster astrocytes. These cells were cultured on cover slides and infected with T. gondii tachyzoites or T. cruzi blood trypomastigotes. Results show that hamster astrocytes are more susceptible to the multiplication of both parasites than rat and mouse cells. There was no statistical difference between the T. gondii infection in rat and mouse astrocytes (p<0.05), and this suggests an important role of other mechanisms or cells in the white rat natural resistance to this parasite. Because the hamster astrocytes are less resistant to these parasites multiplication and not necessarily to the invasion, any difference observed could be due to an intracellular effect: hamster brain astrocytes favor survival and multiplication of these parasites. 2003 artículo científico 0034-7744 https://www.redalyc.org/articulo.oa?id=44911882005 en http://www.redalyc.org/revista.oa?id=449 Revista de Biología Tropical application/pdf Universidad de Costa Rica Revista de Biología Tropical (Costa Rica) Num.3-4 Vol.51 |
| title | In vitro multiplication of Toxoplasma gondii and Trypanosoma cruzi in mouse, rat, and hamster astrocytes |
| topic | Biología rat mouse hamster astrocyte cell culture |
| url | https://www.redalyc.org/articulo.oa?id=44911882005 |