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| Format: | Artículo científico |
| Language: | en |
| Published: |
Universidad de Costa Rica
2007
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| Online Access: | https://www.redalyc.org/articulo.oa?id=44955111 |
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Table of Contents:
- Effect of Echinacea purpurea (Asteraceae) aqueous extract on antibody response to Bothrops asper venom and immune cell response Fernando Chaves Mauricio Chacón Beatriz Badilla Carolina Arévalo Biología adjuvant plant extract Echinacea purpurea murine antivenom antibodies immunostimulatory properties The effect of aqueous extract of Echinacea purpurea roots on the murine antibody response toBothrops asper snake venom in vivo was studied. Three groups were used. Group #1, baseline control, wastreated with snake venom plus PBS. Group #2 was treated with snake venom plus sodium alginate as adjuvant(routine method used at Instituto Clodomiro Picado), and group #3 or experimental group, was treated withsnake venom plus aqueous extract of E. purpurea root as adjuvant. In all groups, the first inoculation was donewith Freunds complete adjuvant (FCA). By the time of the second bleeding, mice in group #3 showed a remarkableincrement in the level of anti-venom antibodies compared with those in groups #1 or #2. In vitro immunecell proliferation as a response to aqueous extract of E. purpurea root was studied using human lymphocytesactivated with different lectins (Con A, PHA and PWM). In all cases, increase in percentage of lymphoproliferationwas greater when E. purpurea root extract was used in addition to individual lectins. Rev. Biol. Trop. 55(1): 113-119. Epub 2007 March. 31. 2007 artículo científico 0034-7744 https://www.redalyc.org/articulo.oa?id=44955111 en http://www.redalyc.org/revista.oa?id=449 Revista de Biología Tropical application/pdf Universidad de Costa Rica Revista de Biología Tropical (Costa Rica) Num.1 Vol.55