Edema induced by Bothrops asper (Squamata: Viperidae) snake venom and its inhibition by Costa Rican plant extracts
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidad de Costa Rica
2006
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| _version_ | 1876454764405850112 |
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| author | Beatriz Badilla |
| author_facet | Beatriz Badilla |
| contents | Edema induced by Bothrops asper (Squamata: Viperidae) snake venom and its inhibition by Costa Rican plant extracts Beatriz Badilla Fernando Chaves Gerardo Mora Luis J. Poveda Biología Anti snake venom plant extracts Bothrops asper edematogenic activity We tested the capacity of leaf (Urera baccifera, Loasa speciosa, Urtica leptuphylla, Chaptalia nutans, and Satureja viminea) and root (Uncaria tomentosa) extracts to inhibit edema induced by Bothrops asper snake venom. Edema-forming activity was studied plethysmographically in the rat hind paw model. Groups of rats were injected intraperitoneally with various doses of each extract and, one hour later, venom was injected subcutaneously in the right hind paw. Edema was assessed at various time intervals. The edematogenic activity was inhibited in those animals that received an injection U. tomentosa, C. nutans or L. speciosa extract. The extract of U. baccifera showed a slight inhibition of the venom effect. Extract from S. viminea and, to a lesser extent that of U. leptuphylla, induced a pro-inflammatory effect, increasing the edema at doses of 250 mg/kg at one and two hours. Rev. Biol. Trop. 54(2): 245-252. Epub 2006 Jun 01. 2006 artículo científico 0034-7744 https://www.redalyc.org/articulo.oa?id=4499844005 en http://www.redalyc.org/revista.oa?id=449 Revista de Biología Tropical application/pdf Universidad de Costa Rica Revista de Biología Tropical (Costa Rica) Num.2 Vol.54 |
| format | Artículo científico |
| id | redalyc_4499844005 |
| institution | Redalyc |
| language | en |
| publishDate | 2006 |
| publisher | Universidad de Costa Rica |
| spellingShingle | Edema induced by Bothrops asper (Squamata: Viperidae) snake venom and its inhibition by Costa Rican plant extracts Beatriz Badilla Biología Anti snake venom plant extracts Bothrops asper edematogenic activity Edema induced by Bothrops asper (Squamata: Viperidae) snake venom and its inhibition by Costa Rican plant extracts Beatriz Badilla Fernando Chaves Gerardo Mora Luis J. Poveda Biología Anti snake venom plant extracts Bothrops asper edematogenic activity We tested the capacity of leaf (Urera baccifera, Loasa speciosa, Urtica leptuphylla, Chaptalia nutans, and Satureja viminea) and root (Uncaria tomentosa) extracts to inhibit edema induced by Bothrops asper snake venom. Edema-forming activity was studied plethysmographically in the rat hind paw model. Groups of rats were injected intraperitoneally with various doses of each extract and, one hour later, venom was injected subcutaneously in the right hind paw. Edema was assessed at various time intervals. The edematogenic activity was inhibited in those animals that received an injection U. tomentosa, C. nutans or L. speciosa extract. The extract of U. baccifera showed a slight inhibition of the venom effect. Extract from S. viminea and, to a lesser extent that of U. leptuphylla, induced a pro-inflammatory effect, increasing the edema at doses of 250 mg/kg at one and two hours. Rev. Biol. Trop. 54(2): 245-252. Epub 2006 Jun 01. 2006 artículo científico 0034-7744 https://www.redalyc.org/articulo.oa?id=4499844005 en http://www.redalyc.org/revista.oa?id=449 Revista de Biología Tropical application/pdf Universidad de Costa Rica Revista de Biología Tropical (Costa Rica) Num.2 Vol.54 |
| title | Edema induced by Bothrops asper (Squamata: Viperidae) snake venom and its inhibition by Costa Rican plant extracts |
| topic | Biología Anti snake venom plant extracts Bothrops asper edematogenic activity |
| url | https://www.redalyc.org/articulo.oa?id=4499844005 |