In vivo magnetic resonance techniques and drug discovery
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| Format: | Artículo científico |
| Langue: | en |
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Sociedade Brasileira de Física
2006
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| _version_ | 1876483359382700032 |
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| author | Nicolau Beckmann |
| author_facet | Nicolau Beckmann |
| contents | In vivo magnetic resonance techniques and drug discovery Nicolau Beckmann Física, Astronomía y Matemáticas Imaging Drug discovery Magnetic resonance The long and resource intensive process of drug discovery and development is confronted with the basicchallenge of providing effective and safe therapies at reasonably low costs. The better the mechanism of adisease is known, the higher the probability to find an appropriate therapy. Also, the better and earlier a diseasecan be diagnosed and characterized, the higher the chance to be able to interfere in this process with a chemicalentity. This reasoning sets the framework for the use of imaging in drug discovery. We discuss the relevanceof magnetic resonance imaging and spectroscopy to derive anatomical, functional, metabolic and target-relatedinformation in the context of pharmacological research in vivo. 2006 artículo científico 0103-9733 https://www.redalyc.org/articulo.oa?id=46436105 en http://www.redalyc.org/revista.oa?id=464 Brazilian Journal of Physics application/pdf Sociedade Brasileira de Física Brazilian Journal of Physics (Brasil) Num.1A Vol.36 |
| format | Artículo científico |
| id | redalyc_46436105 |
| institution | Redalyc |
| language | en |
| publishDate | 2006 |
| publisher | Sociedade Brasileira de Física |
| spellingShingle | In vivo magnetic resonance techniques and drug discovery Nicolau Beckmann Física, Astronomía y Matemáticas Imaging Drug discovery Magnetic resonance In vivo magnetic resonance techniques and drug discovery Nicolau Beckmann Física, Astronomía y Matemáticas Imaging Drug discovery Magnetic resonance The long and resource intensive process of drug discovery and development is confronted with the basicchallenge of providing effective and safe therapies at reasonably low costs. The better the mechanism of adisease is known, the higher the probability to find an appropriate therapy. Also, the better and earlier a diseasecan be diagnosed and characterized, the higher the chance to be able to interfere in this process with a chemicalentity. This reasoning sets the framework for the use of imaging in drug discovery. We discuss the relevanceof magnetic resonance imaging and spectroscopy to derive anatomical, functional, metabolic and target-relatedinformation in the context of pharmacological research in vivo. 2006 artículo científico 0103-9733 https://www.redalyc.org/articulo.oa?id=46436105 en http://www.redalyc.org/revista.oa?id=464 Brazilian Journal of Physics application/pdf Sociedade Brasileira de Física Brazilian Journal of Physics (Brasil) Num.1A Vol.36 |
| title | In vivo magnetic resonance techniques and drug discovery |
| topic | Física, Astronomía y Matemáticas Imaging Drug discovery Magnetic resonance |
| url | https://www.redalyc.org/articulo.oa?id=46436105 |