Bayesian and maximum likelihood inference for the defective Gompertz cure rate model with covariates: an application to the cervical carcinoma study
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidade Federal de Santa Maria
2017
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| _version_ | 1876436694716121088 |
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| author | Milene Regina dos Santos |
| author_facet | Milene Regina dos Santos |
| contents | Bayesian and maximum likelihood inference for the defective Gompertz cure rate model with covariates: an application to the cervical carcinoma study Milene Regina dos Santos Jorge Alberto Achcar Edson Zangiacomi Martinez Estudios Ambientales Survival analysis Bayesian inference Defective distributions Maximum likelihood estimation Modified Gompertz distribution Survival analysis is a class of statistical methods to study the time until the occurrence of a specified event. The usual methods assume that all individuals under study are subjects to the event the interest. However, there are situations where this case is unrealistic. For example, in a clinical research, a proportion of patients could respond favourably to the treatment under investigation and consequently they would not die from the disease. Models based on defective distributions are a suitable way to analyse data with these characteristics. In this paper, we present Bayesian and maximum likelihood inference for the defective Gompertz cure rate model in presence of covariates. An example with application to disease-free survival of women treated for cervical carcinoma is used to illustrate the proposed methodology. In the Bayesian analysis, posterior distributions of parameters are estimated using the Markov chain Monte Carlo (MCMC) method. R, SAS and OpenBUGS codes are provided in an appendix at the end of the paper so that reader can carry out their own analysis. 2017 artículo científico 0100-8307 https://www.redalyc.org/articulo.oa?id=467551029005 https://www.redalyc.org/journal/4675/467551029005/ https://www.redalyc.org/journal/4675/467551029005/html/ https://www.redalyc.org/journal/4675/467551029005/467551029005.epub https://www.redalyc.org/journal/4675/467551029005/movil en http://www.redalyc.org/revista.oa?id=4675 Ciência e Natura application/pdf Universidade Federal de Santa Maria Ciência e Natura (Brasil) Num.2 Vol.39 |
| format | Artículo científico |
| id | redalyc_467551029005 |
| institution | Redalyc |
| language | en |
| publishDate | 2017 |
| publisher | Universidade Federal de Santa Maria |
| spellingShingle | Bayesian and maximum likelihood inference for the defective Gompertz cure rate model with covariates: an application to the cervical carcinoma study Milene Regina dos Santos Estudios Ambientales Survival analysis Bayesian inference Defective distributions Maximum likelihood estimation Modified Gompertz distribution Bayesian and maximum likelihood inference for the defective Gompertz cure rate model with covariates: an application to the cervical carcinoma study Milene Regina dos Santos Jorge Alberto Achcar Edson Zangiacomi Martinez Estudios Ambientales Survival analysis Bayesian inference Defective distributions Maximum likelihood estimation Modified Gompertz distribution Survival analysis is a class of statistical methods to study the time until the occurrence of a specified event. The usual methods assume that all individuals under study are subjects to the event the interest. However, there are situations where this case is unrealistic. For example, in a clinical research, a proportion of patients could respond favourably to the treatment under investigation and consequently they would not die from the disease. Models based on defective distributions are a suitable way to analyse data with these characteristics. In this paper, we present Bayesian and maximum likelihood inference for the defective Gompertz cure rate model in presence of covariates. An example with application to disease-free survival of women treated for cervical carcinoma is used to illustrate the proposed methodology. In the Bayesian analysis, posterior distributions of parameters are estimated using the Markov chain Monte Carlo (MCMC) method. R, SAS and OpenBUGS codes are provided in an appendix at the end of the paper so that reader can carry out their own analysis. 2017 artículo científico 0100-8307 https://www.redalyc.org/articulo.oa?id=467551029005 https://www.redalyc.org/journal/4675/467551029005/ https://www.redalyc.org/journal/4675/467551029005/html/ https://www.redalyc.org/journal/4675/467551029005/467551029005.epub https://www.redalyc.org/journal/4675/467551029005/movil en http://www.redalyc.org/revista.oa?id=4675 Ciência e Natura application/pdf Universidade Federal de Santa Maria Ciência e Natura (Brasil) Num.2 Vol.39 |
| title | Bayesian and maximum likelihood inference for the defective Gompertz cure rate model with covariates: an application to the cervical carcinoma study |
| topic | Estudios Ambientales Survival analysis Bayesian inference Defective distributions Maximum likelihood estimation Modified Gompertz distribution |
| url | https://www.redalyc.org/articulo.oa?id=467551029005 https://www.redalyc.org/journal/4675/467551029005/ https://www.redalyc.org/journal/4675/467551029005/html/ https://www.redalyc.org/journal/4675/467551029005/467551029005.epub https://www.redalyc.org/journal/4675/467551029005/movil |