In vitro assessment of murine melanoma cells sensitivity to non-thermal atmospheric plasma
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| Format: | Artículo científico |
| Language: | en |
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Universidad Nacional Autónoma de México
2019
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| _version_ | 1876449082232274944 |
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| author | Jorge Humberto Serment Guerrero |
| author_facet | Jorge Humberto Serment Guerrero |
| contents | In vitro assessment of murine melanoma cells sensitivity to non-thermal atmospheric plasma Jorge Humberto Serment Guerrero Karina Giron Romero Régulo López-Callejas Rosendo Peña-Eguiluz Ingeniería Non melanoma genotoxicity thermal plasma Melanoma is a dangerous skin cancer incidence of which has been increasing over the past years, so is important the search for new treatments. The purpose of the present work is to evaluate the relative sensitivity of a melanoma cell line to helium-generated non-thermal plasma. For that, three cell types were used (murine melanoma B16 cells, mouse embryo fibroblasts, and peripherical blood lymphocytes) and both cytotoxicity and genotoxicity were evaluated. The lethality produced by no-thermal plasma was higher in melanoma mouse cells compared with lymphocytes and fibroblasts. Accordingly, B16 cells showed higher levels of DNA fragmentation by this agent. Overall, the results suggest that non-thermal plasma has the potential to become a good alternative for treating skin cancer. 2019 artículo científico 1665-6423 https://www.redalyc.org/articulo.oa?id=47471659005 https://www.redalyc.org/journal/474/47471659005/ https://www.redalyc.org/journal/474/47471659005/html/ https://www.redalyc.org/journal/474/47471659005/47471659005.epub https://www.redalyc.org/journal/474/47471659005/movil 10.22201/icat.16656423.2019.17.3.810 en http://www.redalyc.org/revista.oa?id=474 Journal of Applied Research and Technology application/pdf Universidad Nacional Autónoma de México Journal of Applied Research and Technology (México) Num.3 Vol.17 |
| format | Artículo científico |
| id | redalyc_47471659005 |
| institution | Redalyc |
| language | en |
| publishDate | 2019 |
| publisher | Universidad Nacional Autónoma de México |
| spellingShingle | In vitro assessment of murine melanoma cells sensitivity to non-thermal atmospheric plasma Jorge Humberto Serment Guerrero Ingeniería Non melanoma genotoxicity thermal plasma In vitro assessment of murine melanoma cells sensitivity to non-thermal atmospheric plasma Jorge Humberto Serment Guerrero Karina Giron Romero Régulo López-Callejas Rosendo Peña-Eguiluz Ingeniería Non melanoma genotoxicity thermal plasma Melanoma is a dangerous skin cancer incidence of which has been increasing over the past years, so is important the search for new treatments. The purpose of the present work is to evaluate the relative sensitivity of a melanoma cell line to helium-generated non-thermal plasma. For that, three cell types were used (murine melanoma B16 cells, mouse embryo fibroblasts, and peripherical blood lymphocytes) and both cytotoxicity and genotoxicity were evaluated. The lethality produced by no-thermal plasma was higher in melanoma mouse cells compared with lymphocytes and fibroblasts. Accordingly, B16 cells showed higher levels of DNA fragmentation by this agent. Overall, the results suggest that non-thermal plasma has the potential to become a good alternative for treating skin cancer. 2019 artículo científico 1665-6423 https://www.redalyc.org/articulo.oa?id=47471659005 https://www.redalyc.org/journal/474/47471659005/ https://www.redalyc.org/journal/474/47471659005/html/ https://www.redalyc.org/journal/474/47471659005/47471659005.epub https://www.redalyc.org/journal/474/47471659005/movil 10.22201/icat.16656423.2019.17.3.810 en http://www.redalyc.org/revista.oa?id=474 Journal of Applied Research and Technology application/pdf Universidad Nacional Autónoma de México Journal of Applied Research and Technology (México) Num.3 Vol.17 |
| title | In vitro assessment of murine melanoma cells sensitivity to non-thermal atmospheric plasma |
| topic | Ingeniería Non melanoma genotoxicity thermal plasma |
| url | https://www.redalyc.org/articulo.oa?id=47471659005 https://www.redalyc.org/journal/474/47471659005/ https://www.redalyc.org/journal/474/47471659005/html/ https://www.redalyc.org/journal/474/47471659005/47471659005.epub https://www.redalyc.org/journal/474/47471659005/movil |