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| Format: | Artículo científico |
| Language: | en |
| Published: |
Sociedad Química de México
2014
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| Online Access: | https://www.redalyc.org/articulo.oa?id=47535733009 |
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Table of Contents:
- Volatile Constituents Identified in Hexane Extract of Citrus sinensis Peel and Anti-Mycobacterial Tuberculosis Activity of Some of its Constituents Patricia C. Esquivel-Ferriño Aldo F. Clemente-Soto Mayela Y. Ramírez-Cabriales Elvira Garza-González Laura Álvarez María del Rayo Camacho-Corona Multidisciplinaria (Ciencias Naturales y Exactas) GC MS anti TB compounds Citrus sinensis Tuberculosis (TB) is a great cause of morbidity and mortal - ity around the world. The increasing incidence of multidrug-resistant (MDR) Mycobacterium tuberculosis and co-infection TB-AIDS led to the need to develop new TB drugs, and plants could be a source of them. The hexane extract of Citrus sinensis with anti-TB activity was analyzed by GC-MS. This analysis showed the presence of 40 vola - tile components, including monoterpenes (81.74%), sesquiterpenes (1.32%), fatty acids (1.15%), and some other oxygenated non-aromatic compounds (15.73%). Some identified compounds were tested against M. tuberculosis H37Rv, and one clinical isolated MDR M. tuberculo - sis strain. Results showed that palmitic acid, decanal, caryophyllene oxide, and cis -limonene oxide contributed to the anti-TB activity of hexane extract of C. sinensis peel. 2014 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47535733009 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.4 Vol.58