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1. Verfasser: Jazmín Gómez-Gutiérrez
Format: Artículo científico
Sprache:en
Veröffentlicht: Sociedad Química de México 2015
Schlagworte:
Online-Zugang:https://www.redalyc.org/articulo.oa?id=47539242003
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author Jazmín Gómez-Gutiérrez
author_facet Jazmín Gómez-Gutiérrez
contents Preparation of (+)- and (−)- B-phenyl- and B-(4-chlorophenyl)-y-butyrolactones: Key Intermediates in the Synthesis of B-phenyl-GABA and Baclofen. Jazmín Gómez-Gutiérrez Myriam Meléndez-Rodríguez Óscar R. Suárez-Castillo Luis E. Castelán - Duarte Manuel J. Fragoso-Vázquez Erick López-Vázquez Maricruz Sánchez-Zavala Multidisciplinaria (Ciencias Naturales y Exactas) Resolution Diastereoisomeric4 hydroxybutyramides Phenylγbutyrolactones Thepreparationofβ-phenyl-andβ-(4-chlorophenyl)-γ-bu-tyrolactones( ± )-3and( ± )-4andtheirresolutiontothecorrespond-ing(+)-(S)-3, (−)-(R)-3and(+)-(S)-4, (−)-(R)-4throughformation,flashcolumnchromatographyseparationandsubsequenthydrolysisofdiastereoisomeric4-hydroxybutyramides(2’R,3S)-5,(2’R,3R)-5,(2’R,3S)-6and(2’R,3R)-6isdescribed.Theabsoluteconfigurationassignmentofenantiopure3and4wassupportedbyX-raycrystal-lographicstructuresof(2’R,3R)-5,(2’R,3S)-6and(2’R,3R)-6 2015 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47539242003 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.1 Vol.59
format Artículo científico
id redalyc_47539242003
language en
publishDate 2015
publisher Sociedad Química de México
spellingShingle Preparation of (+)- and (−)- B-phenyl- and B-(4-chlorophenyl)-y-butyrolactones: Key Intermediates in the Synthesis of B-phenyl-GABA and Baclofen.
Jazmín Gómez-Gutiérrez
Multidisciplinaria (Ciencias Naturales y Exactas)
Resolution
Diastereoisomeric4
hydroxybutyramides
Phenylγbutyrolactones
Preparation of (+)- and (−)- B-phenyl- and B-(4-chlorophenyl)-y-butyrolactones: Key Intermediates in the Synthesis of B-phenyl-GABA and Baclofen. Jazmín Gómez-Gutiérrez Myriam Meléndez-Rodríguez Óscar R. Suárez-Castillo Luis E. Castelán - Duarte Manuel J. Fragoso-Vázquez Erick López-Vázquez Maricruz Sánchez-Zavala Multidisciplinaria (Ciencias Naturales y Exactas) Resolution Diastereoisomeric4 hydroxybutyramides Phenylγbutyrolactones Thepreparationofβ-phenyl-andβ-(4-chlorophenyl)-γ-bu-tyrolactones( ± )-3and( ± )-4andtheirresolutiontothecorrespond-ing(+)-(S)-3, (−)-(R)-3and(+)-(S)-4, (−)-(R)-4throughformation,flashcolumnchromatographyseparationandsubsequenthydrolysisofdiastereoisomeric4-hydroxybutyramides(2’R,3S)-5,(2’R,3R)-5,(2’R,3S)-6and(2’R,3R)-6isdescribed.Theabsoluteconfigurationassignmentofenantiopure3and4wassupportedbyX-raycrystal-lographicstructuresof(2’R,3R)-5,(2’R,3S)-6and(2’R,3R)-6 2015 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47539242003 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.1 Vol.59
title Preparation of (+)- and (−)- B-phenyl- and B-(4-chlorophenyl)-y-butyrolactones: Key Intermediates in the Synthesis of B-phenyl-GABA and Baclofen.
topic Multidisciplinaria (Ciencias Naturales y Exactas)
Resolution
Diastereoisomeric4
hydroxybutyramides
Phenylγbutyrolactones
url https://www.redalyc.org/articulo.oa?id=47539242003