Optimization of Extraction Conditions for Flavonoids of Physalis alkekengi var. franchetii Stems by Response Surface Methodology and Inhibition of Acetylcholinesterase Activity
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| Format: | Artículo científico |
| Language: | en |
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Sociedad Química de México
2015
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| _version_ | 1876454430929321984 |
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| author | Xue-gui Liu |
| author_facet | Xue-gui Liu |
| contents | Optimization of Extraction Conditions for Flavonoids of Physalis alkekengi var. franchetii Stems by Response Surface Methodology and Inhibition of Acetylcholinesterase Activity Xue-gui Liu Fu-yu Jiang Pin-yi Gao Mei Jin Di Yang Zhong-feng Nian Zhen-xue Zhang Multidisciplinaria (Ciencias Naturales y Exactas) var Microwave Flavonoids franchetii Stems Physalis alkekengi The microwave-assisted extraction conditions of flavonoids in Physalis alkekengi. var. franchetii stems were optimized using a L33 Box-Behnken Design. The optimized extraction conditions were determined as follows: 60% for the ethanol concentration, 12.4 for the liquid-to-solid ratio, and 531.4 W for the microwave power, respectively. The yield of the extract obtained under the optimized conditions was 3.85 mg g-1 which was close to the predicted value. In addition, the extract exhibited potent acetylcholinesterase inhibitory activity, with the IC50 value of 11.61 μg mL-1 and a maximal inhibition ratio 89.81%. Both the yield and activity were better than reflux extraction. 2015 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47539242011 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.1 Vol.59 |
| format | Artículo científico |
| id | redalyc_47539242011 |
| institution | Redalyc |
| language | en |
| publishDate | 2015 |
| publisher | Sociedad Química de México |
| spellingShingle | Optimization of Extraction Conditions for Flavonoids of Physalis alkekengi var. franchetii Stems by Response Surface Methodology and Inhibition of Acetylcholinesterase Activity Xue-gui Liu Multidisciplinaria (Ciencias Naturales y Exactas) var Microwave Flavonoids franchetii Stems Physalis alkekengi Optimization of Extraction Conditions for Flavonoids of Physalis alkekengi var. franchetii Stems by Response Surface Methodology and Inhibition of Acetylcholinesterase Activity Xue-gui Liu Fu-yu Jiang Pin-yi Gao Mei Jin Di Yang Zhong-feng Nian Zhen-xue Zhang Multidisciplinaria (Ciencias Naturales y Exactas) var Microwave Flavonoids franchetii Stems Physalis alkekengi The microwave-assisted extraction conditions of flavonoids in Physalis alkekengi. var. franchetii stems were optimized using a L33 Box-Behnken Design. The optimized extraction conditions were determined as follows: 60% for the ethanol concentration, 12.4 for the liquid-to-solid ratio, and 531.4 W for the microwave power, respectively. The yield of the extract obtained under the optimized conditions was 3.85 mg g-1 which was close to the predicted value. In addition, the extract exhibited potent acetylcholinesterase inhibitory activity, with the IC50 value of 11.61 μg mL-1 and a maximal inhibition ratio 89.81%. Both the yield and activity were better than reflux extraction. 2015 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47539242011 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.1 Vol.59 |
| title | Optimization of Extraction Conditions for Flavonoids of Physalis alkekengi var. franchetii Stems by Response Surface Methodology and Inhibition of Acetylcholinesterase Activity |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) var Microwave Flavonoids franchetii Stems Physalis alkekengi |
| url | https://www.redalyc.org/articulo.oa?id=47539242011 |