A New Approach for the Synthesis of the Cyclohexene Core of Anthracyclines and Milbemycins
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Sociedad Química de México
2000
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| _version_ | 1876450976884326400 |
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| author | Joaquín Tamariz |
| author_facet | Joaquín Tamariz |
| contents | A New Approach for the Synthesis of the Cyclohexene Core of Anthracyclines and Milbemycins Joaquín Tamariz Raúl Aguilar Alicia Reyes Arturo Orduña Gerardo Zepeda Roderick W. Bates Multidisciplinaria (Ciencias Naturales y Exactas) Diels Alder milbemycins anthracyclines cyclohexene core A new synthesis of the cyclohexene core of the anthracyclinesand milbemycins antibiotics is described, using 3-p-nitrobenzoyloxy-3-buten-2-one (9a) as an efficient dienophile in Diels-Alderreactions with substituted dienes. Allylic functionalization andepimerization of the cycloadducts led, in moderate overall yields, tothe corresponding related cyclohexene A-rings of aclacinomycin, aand b-rhodomycins, and the cyclohexene moiety of milbemycins b1and E. 2000 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47544205 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.2 Vol.44 |
| format | Artículo científico |
| id | redalyc_47544205 |
| institution | Redalyc |
| language | en |
| publishDate | 2000 |
| publisher | Sociedad Química de México |
| spellingShingle | A New Approach for the Synthesis of the Cyclohexene Core of Anthracyclines and Milbemycins Joaquín Tamariz Multidisciplinaria (Ciencias Naturales y Exactas) Diels Alder milbemycins anthracyclines cyclohexene core A New Approach for the Synthesis of the Cyclohexene Core of Anthracyclines and Milbemycins Joaquín Tamariz Raúl Aguilar Alicia Reyes Arturo Orduña Gerardo Zepeda Roderick W. Bates Multidisciplinaria (Ciencias Naturales y Exactas) Diels Alder milbemycins anthracyclines cyclohexene core A new synthesis of the cyclohexene core of the anthracyclinesand milbemycins antibiotics is described, using 3-p-nitrobenzoyloxy-3-buten-2-one (9a) as an efficient dienophile in Diels-Alderreactions with substituted dienes. Allylic functionalization andepimerization of the cycloadducts led, in moderate overall yields, tothe corresponding related cyclohexene A-rings of aclacinomycin, aand b-rhodomycins, and the cyclohexene moiety of milbemycins b1and E. 2000 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47544205 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.2 Vol.44 |
| title | A New Approach for the Synthesis of the Cyclohexene Core of Anthracyclines and Milbemycins |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) Diels Alder milbemycins anthracyclines cyclohexene core |
| url | https://www.redalyc.org/articulo.oa?id=47544205 |