On the Toxicity of the Aromatic Diamines and their Tetramethylcarboxylic Acid Derivatives
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| Format: | Artículo científico |
| Sprache: | en |
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Sociedad Química de México
2000
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| _version_ | 1876470093588725760 |
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| author | Pedro Gili |
| author_facet | Pedro Gili |
| contents | On the Toxicity of the Aromatic Diamines and their Tetramethylcarboxylic Acid Derivatives Pedro Gili Alfredo Mederos Multidisciplinaria (Ciencias Naturales y Exactas) toxicity aromatic diamines Theoretical program tetramethylcarboxylic acid derivatives The use of the theoretical PALLAS 3.0 program, to studythe toxic behaviour of tetramethylcarboxylic acids, potential pharmaceuticalsderived from o-phenylenediamines, indicates that o-phenylenediaminesare highly toxic (level 1), while the tetramethycarboxylicacid derivatives (o-PhDTA and 3,4-TDTA) are slightly toxic,similar to EDTA (level 3). Therefore these ligands o-PhDTA and 3,4-TDTA, similar to EDTA, can be used as sequestering agents of toxicmetals and overload of essential metals in biological systems. 2000 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47544208 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.2 Vol.44 |
| format | Artículo científico |
| id | redalyc_47544208 |
| institution | Redalyc |
| language | en |
| publishDate | 2000 |
| publisher | Sociedad Química de México |
| spellingShingle | On the Toxicity of the Aromatic Diamines and their Tetramethylcarboxylic Acid Derivatives Pedro Gili Multidisciplinaria (Ciencias Naturales y Exactas) toxicity aromatic diamines Theoretical program tetramethylcarboxylic acid derivatives On the Toxicity of the Aromatic Diamines and their Tetramethylcarboxylic Acid Derivatives Pedro Gili Alfredo Mederos Multidisciplinaria (Ciencias Naturales y Exactas) toxicity aromatic diamines Theoretical program tetramethylcarboxylic acid derivatives The use of the theoretical PALLAS 3.0 program, to studythe toxic behaviour of tetramethylcarboxylic acids, potential pharmaceuticalsderived from o-phenylenediamines, indicates that o-phenylenediaminesare highly toxic (level 1), while the tetramethycarboxylicacid derivatives (o-PhDTA and 3,4-TDTA) are slightly toxic,similar to EDTA (level 3). Therefore these ligands o-PhDTA and 3,4-TDTA, similar to EDTA, can be used as sequestering agents of toxicmetals and overload of essential metals in biological systems. 2000 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47544208 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.2 Vol.44 |
| title | On the Toxicity of the Aromatic Diamines and their Tetramethylcarboxylic Acid Derivatives |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) toxicity aromatic diamines Theoretical program tetramethylcarboxylic acid derivatives |
| url | https://www.redalyc.org/articulo.oa?id=47544208 |