Microwave-assisted synthesis of ethyl 7-chloro-4-oxo-l,4-dihydro-1,8-naphthyridine-3-carboxylate by the Grohe-Heitzer reaction
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| Format: | Artículo científico |
| Language: | en |
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Sociedad Química de México
2017
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| _version_ | 1876437073733353472 |
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| author | Socorro Leyva-Ramos |
| author_facet | Socorro Leyva-Ramos |
| contents | Microwave-assisted synthesis of ethyl 7-chloro-4-oxo-l,4-dihydro-1,8-naphthyridine-3-carboxylate by the Grohe-Heitzer reaction Socorro Leyva-Ramos Elisa Leyva Jaime Cardoso-Ortiz Hiram Hernández-López Multidisciplinaria (Ciencias Naturales y Exactas) Grohe naphtyridone Heitzer reaction microwave iradiation tautomeric equilibrium A simple and efficient two-step method was implemented for the synthesis of ethyl 7-chloro-4-oxo-1,4-dihydro-1,8-naphthyri - dine-3-carboxylate. Comparing with the reported Grohe-Heitzer reac - tion, the time and the reaction steps have been reduced using microwave irradiation. This compound is an important intermediate for the preparation of naphthyridone derivatives which have received significant attention due to their broad spectrum of biological activity. 2017 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47551118007 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.1 Vol.61 |
| format | Artículo científico |
| id | redalyc_47551118007 |
| institution | Redalyc |
| language | en |
| publishDate | 2017 |
| publisher | Sociedad Química de México |
| spellingShingle | Microwave-assisted synthesis of ethyl 7-chloro-4-oxo-l,4-dihydro-1,8-naphthyridine-3-carboxylate by the Grohe-Heitzer reaction Socorro Leyva-Ramos Multidisciplinaria (Ciencias Naturales y Exactas) Grohe naphtyridone Heitzer reaction microwave iradiation tautomeric equilibrium Microwave-assisted synthesis of ethyl 7-chloro-4-oxo-l,4-dihydro-1,8-naphthyridine-3-carboxylate by the Grohe-Heitzer reaction Socorro Leyva-Ramos Elisa Leyva Jaime Cardoso-Ortiz Hiram Hernández-López Multidisciplinaria (Ciencias Naturales y Exactas) Grohe naphtyridone Heitzer reaction microwave iradiation tautomeric equilibrium A simple and efficient two-step method was implemented for the synthesis of ethyl 7-chloro-4-oxo-1,4-dihydro-1,8-naphthyri - dine-3-carboxylate. Comparing with the reported Grohe-Heitzer reac - tion, the time and the reaction steps have been reduced using microwave irradiation. This compound is an important intermediate for the preparation of naphthyridone derivatives which have received significant attention due to their broad spectrum of biological activity. 2017 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47551118007 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.1 Vol.61 |
| title | Microwave-assisted synthesis of ethyl 7-chloro-4-oxo-l,4-dihydro-1,8-naphthyridine-3-carboxylate by the Grohe-Heitzer reaction |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) Grohe naphtyridone Heitzer reaction microwave iradiation tautomeric equilibrium |
| url | https://www.redalyc.org/articulo.oa?id=47551118007 |