Coumarin Derivatives from Loeselia mexicana. Determination of the Anxiolytic Effect of Daphnoretin on Elevated Plus-maze
Fuente:
Redalyc
Guardado en:
| Autor principal: | |
|---|---|
| Formato: | Artículo científico |
| Lenguaje: | en |
| Publicado: |
Sociedad Química de México
2007
|
| Materias: | |
| Acceso en línea: | |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| _version_ | 1876458065025302528 |
|---|---|
| author | Víctor M. Navarro |
| author_facet | Víctor M. Navarro |
| contents | Coumarin Derivatives from Loeselia mexicana. Determination of the Anxiolytic Effect of Daphnoretin on Elevated Plus-maze Víctor M. Navarro Maribel Herrera L. Gerardo Zepeda Gabriela Rojas Multidisciplinaria (Ciencias Naturales y Exactas) anxiety daphnoretin acetyldaphnoretin elevated plus maze 13C NMR chemical shift The bis-coumarin daphnoretin (1) and its monomeric precursorsscopoletin (3) and umbelliferone (4) were isolated for the firsttime from L. mexicana, a vegetal species used in Mexican traditionalmedicine. The unambiguous 13C NMR chemical shifts assignmentsof daphnoretin (1) and its acetyl derivative 2 were achieved throughone-bond (gHMQC) and long-distance (gHMBC) heteronuclear correlations.The crude hydroalcoholic extract and pure daphnoretin 1obtained from this plant, showed anxiolytic effect in male ICR miceexposed to elevated plus-maze. Different doses of daphnoretin (1)were not able to modify the spontaneous locomotor activity measuredin the open field test. This is the first report regarding to the anxiolyticeffect of daphnoretin (1). 2007 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47551405 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.4 Vol.51 |
| format | Artículo científico |
| id | redalyc_47551405 |
| institution | Redalyc |
| language | en |
| publishDate | 2007 |
| publisher | Sociedad Química de México |
| spellingShingle | Coumarin Derivatives from Loeselia mexicana. Determination of the Anxiolytic Effect of Daphnoretin on Elevated Plus-maze Víctor M. Navarro Multidisciplinaria (Ciencias Naturales y Exactas) anxiety daphnoretin acetyldaphnoretin elevated plus maze 13C NMR chemical shift Coumarin Derivatives from Loeselia mexicana. Determination of the Anxiolytic Effect of Daphnoretin on Elevated Plus-maze Víctor M. Navarro Maribel Herrera L. Gerardo Zepeda Gabriela Rojas Multidisciplinaria (Ciencias Naturales y Exactas) anxiety daphnoretin acetyldaphnoretin elevated plus maze 13C NMR chemical shift The bis-coumarin daphnoretin (1) and its monomeric precursorsscopoletin (3) and umbelliferone (4) were isolated for the firsttime from L. mexicana, a vegetal species used in Mexican traditionalmedicine. The unambiguous 13C NMR chemical shifts assignmentsof daphnoretin (1) and its acetyl derivative 2 were achieved throughone-bond (gHMQC) and long-distance (gHMBC) heteronuclear correlations.The crude hydroalcoholic extract and pure daphnoretin 1obtained from this plant, showed anxiolytic effect in male ICR miceexposed to elevated plus-maze. Different doses of daphnoretin (1)were not able to modify the spontaneous locomotor activity measuredin the open field test. This is the first report regarding to the anxiolyticeffect of daphnoretin (1). 2007 artículo científico 1870-249X https://www.redalyc.org/articulo.oa?id=47551405 en http://www.redalyc.org/revista.oa?id=475 Journal of the Mexican Chemical Society application/pdf Sociedad Química de México Journal of the Mexican Chemical Society (México) Num.4 Vol.51 |
| title | Coumarin Derivatives from Loeselia mexicana. Determination of the Anxiolytic Effect of Daphnoretin on Elevated Plus-maze |
| topic | Multidisciplinaria (Ciencias Naturales y Exactas) anxiety daphnoretin acetyldaphnoretin elevated plus maze 13C NMR chemical shift |
| url | https://www.redalyc.org/articulo.oa?id=47551405 |