Reactividad cruzada en sinusitis alérgica fúngica. Reporte de caso

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Auteur principal: Sandra Nora González-Díaz
Format: Artículo científico
Langue:es
Publié: Colegio Mexicano de Inmunología Clínica y Alergia, A.C. 2016
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author Sandra Nora González-Díaz
author_facet Sandra Nora González-Díaz
contents Reactividad cruzada en sinusitis alérgica fúngica. Reporte de caso Sandra Nora González-Díaz Alfredo Arias-Cruz Dulce María Rivero-Arias Alma Belén Partida-Ortega Bárbara Elizondo-Villarreal Jesús Arturo Ibarra-Chávez Lissette Ramos-Valencia Olga Patricia Monge-Ortega Carlos Macouzet-Sánchez María del Rocío Salinas-Díaz Medicina Aspergillus Rhinosinusitis Corticosteroids Allergic fungal sinusitis Background: The presence of allergic mucin in allergic fungal sinusitis (AFS) is a manifestation that identifies it as a hypersensitivity process. AFS has a phenomenon of cross-reactivity to IgE- bound proteins having at least two shared epitopes. Case report: A 13-year-old male with nasal obstructive symptoms of three years of evolution. An obstructive mass was identified in the sinuses through physical examination and CT. In endoscopic surgery, the left nostril polyp was identified with the macroscopic appearance of allergic mucin; the polyp was resected. Final histopathological examination using periodic acid-Schiff and Grocott’s methenamine silver staining indicated Aspergillus. Two weeks after surgery, percutaneous tests showed sensitization to Alternaria, Helminthosporium sativum, and Deramatophagoides farianae with negativity to Aspergillus fumigatus. Conclusions: The absence of significant titers of specific IgE antibodies to Aspergillus fumigatus was the evidence that the hypersensitivity response was triggered by a pathogen other than that isolated in histopathological study, which coupled with positive tests for other fungi may be explained by the cross-reactivity phenomenon in a phenomenon of likely hypersensitivity. 2016 artículo científico 0002-5151 https://www.redalyc.org/articulo.oa?id=486755025005 es http://www.redalyc.org/revista.oa?id=4867 Revista Alergia México application/pdf Colegio Mexicano de Inmunología Clínica y Alergia, A.C. Revista Alergia México (México) Num.3 Vol.63
format Artículo científico
id redalyc_486755025005
institution Redalyc
language es
publishDate 2016
publisher Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
spellingShingle Reactividad cruzada en sinusitis alérgica fúngica. Reporte de caso
Sandra Nora González-Díaz
Medicina
Aspergillus
Rhinosinusitis
Corticosteroids
Allergic fungal sinusitis
Reactividad cruzada en sinusitis alérgica fúngica. Reporte de caso Sandra Nora González-Díaz Alfredo Arias-Cruz Dulce María Rivero-Arias Alma Belén Partida-Ortega Bárbara Elizondo-Villarreal Jesús Arturo Ibarra-Chávez Lissette Ramos-Valencia Olga Patricia Monge-Ortega Carlos Macouzet-Sánchez María del Rocío Salinas-Díaz Medicina Aspergillus Rhinosinusitis Corticosteroids Allergic fungal sinusitis Background: The presence of allergic mucin in allergic fungal sinusitis (AFS) is a manifestation that identifies it as a hypersensitivity process. AFS has a phenomenon of cross-reactivity to IgE- bound proteins having at least two shared epitopes. Case report: A 13-year-old male with nasal obstructive symptoms of three years of evolution. An obstructive mass was identified in the sinuses through physical examination and CT. In endoscopic surgery, the left nostril polyp was identified with the macroscopic appearance of allergic mucin; the polyp was resected. Final histopathological examination using periodic acid-Schiff and Grocott’s methenamine silver staining indicated Aspergillus. Two weeks after surgery, percutaneous tests showed sensitization to Alternaria, Helminthosporium sativum, and Deramatophagoides farianae with negativity to Aspergillus fumigatus. Conclusions: The absence of significant titers of specific IgE antibodies to Aspergillus fumigatus was the evidence that the hypersensitivity response was triggered by a pathogen other than that isolated in histopathological study, which coupled with positive tests for other fungi may be explained by the cross-reactivity phenomenon in a phenomenon of likely hypersensitivity. 2016 artículo científico 0002-5151 https://www.redalyc.org/articulo.oa?id=486755025005 es http://www.redalyc.org/revista.oa?id=4867 Revista Alergia México application/pdf Colegio Mexicano de Inmunología Clínica y Alergia, A.C. Revista Alergia México (México) Num.3 Vol.63
title Reactividad cruzada en sinusitis alérgica fúngica. Reporte de caso
topic Medicina
Aspergillus
Rhinosinusitis
Corticosteroids
Allergic fungal sinusitis
url https://www.redalyc.org/articulo.oa?id=486755025005