Clínica de inmunodeficiencias primarias en adultos. Experiencia en un hospital de tercer nivel
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| Format: | Artículo científico |
| Language: | es |
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Colegio Mexicano de Inmunología Clínica y Alergia, A.C.
2016
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| author | Julio César Cambray-Gutiérrez |
| author_facet | Julio César Cambray-Gutiérrez |
| contents | Clínica de inmunodeficiencias primarias en adultos. Experiencia en un hospital de tercer nivel Julio César Cambray-Gutiérrez Diana Andrea Herrera-Sánchez Lizbeth Blancas-Galicia Patricia María O’Farrill-Romanillos Medicina Bruton agammaglobulinemia Primary immunodeficiencies Humoral immunodeficiencies Common variable immunodeficiency Background: Primary immunodeficiencies (PID) are characterized by alteration of the components of the immune system. Humoral deficiencies represent 50%. The most common are selective IgA deficiency, Bruton agammaglobulinemia, and common variable immunodeficiency (CVID). Objective: To describe the epidemiological and clinical characteristics of adults with humoral PID, cared for in a Primary Humoral Immunodeficiencies Clinic. Methods: A descriptive cross-sectional study that included a year of analysis, including 35 patients with humoral PID, 31 with CVID, and 4 with Bruton agammaglobulinemia. Data were analyzed with descriptive statistics. Results: Of 35 patients studied, 31 had CVID (88.5%) and 4 (11.5%) Bruton agammaglobulinemia; 21 were men and 14 women. The age at onset of symptoms was 22.7 years, and the delay in diagnosis was 7.2 years. 11.4% of CVID patients died during the study; 4 had malignancies, 22.8% autoimmune diseases, and 48.5% gastrointestinal disorders. Patients with Bruton agammaglobulinemia presented no comorbidities. Conclusions: Unlike reports in the literature, in the study group, CVID was the most common cause of humoral PID, predominantly in men; the most common gastrointestinal disorder was intestinal functional disorder. 2016 artículo científico 0002-5151 https://www.redalyc.org/articulo.oa?id=486755026002 es http://www.redalyc.org/revista.oa?id=4867 Revista Alergia México application/pdf Colegio Mexicano de Inmunología Clínica y Alergia, A.C. Revista Alergia México (México) Num.4 Vol.63 |
| format | Artículo científico |
| id | redalyc_486755026002 |
| institution | Redalyc |
| language | es |
| publishDate | 2016 |
| publisher | Colegio Mexicano de Inmunología Clínica y Alergia, A.C. |
| spellingShingle | Clínica de inmunodeficiencias primarias en adultos. Experiencia en un hospital de tercer nivel Julio César Cambray-Gutiérrez Medicina Bruton agammaglobulinemia Primary immunodeficiencies Humoral immunodeficiencies Common variable immunodeficiency Clínica de inmunodeficiencias primarias en adultos. Experiencia en un hospital de tercer nivel Julio César Cambray-Gutiérrez Diana Andrea Herrera-Sánchez Lizbeth Blancas-Galicia Patricia María O’Farrill-Romanillos Medicina Bruton agammaglobulinemia Primary immunodeficiencies Humoral immunodeficiencies Common variable immunodeficiency Background: Primary immunodeficiencies (PID) are characterized by alteration of the components of the immune system. Humoral deficiencies represent 50%. The most common are selective IgA deficiency, Bruton agammaglobulinemia, and common variable immunodeficiency (CVID). Objective: To describe the epidemiological and clinical characteristics of adults with humoral PID, cared for in a Primary Humoral Immunodeficiencies Clinic. Methods: A descriptive cross-sectional study that included a year of analysis, including 35 patients with humoral PID, 31 with CVID, and 4 with Bruton agammaglobulinemia. Data were analyzed with descriptive statistics. Results: Of 35 patients studied, 31 had CVID (88.5%) and 4 (11.5%) Bruton agammaglobulinemia; 21 were men and 14 women. The age at onset of symptoms was 22.7 years, and the delay in diagnosis was 7.2 years. 11.4% of CVID patients died during the study; 4 had malignancies, 22.8% autoimmune diseases, and 48.5% gastrointestinal disorders. Patients with Bruton agammaglobulinemia presented no comorbidities. Conclusions: Unlike reports in the literature, in the study group, CVID was the most common cause of humoral PID, predominantly in men; the most common gastrointestinal disorder was intestinal functional disorder. 2016 artículo científico 0002-5151 https://www.redalyc.org/articulo.oa?id=486755026002 es http://www.redalyc.org/revista.oa?id=4867 Revista Alergia México application/pdf Colegio Mexicano de Inmunología Clínica y Alergia, A.C. Revista Alergia México (México) Num.4 Vol.63 |
| title | Clínica de inmunodeficiencias primarias en adultos. Experiencia en un hospital de tercer nivel |
| topic | Medicina Bruton agammaglobulinemia Primary immunodeficiencies Humoral immunodeficiencies Common variable immunodeficiency |
| url | https://www.redalyc.org/articulo.oa?id=486755026002 |