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Bibliographic Details
Main Author:	Mónica María Molina-Sáenz
Format:	Artículo científico
Language:	es
Published:	Colegio Mexicano de Inmunología Clínica y Alergia, A.C. 2017
Subjects:	Medicina Alergia Inmunoterapia Dermatophagoides Enfermedad respiratoria
Online Access:	https://www.redalyc.org/articulo.oa?id=486755082007 https://www.redalyc.org/journal/4867/486755082007/ https://www.redalyc.org/journal/4867/486755082007/html/ https://www.redalyc.org/journal/4867/486755082007/486755082007.epub https://www.redalyc.org/journal/4867/486755082007/movil
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Seguridad de la inmunoterapia subcutánea con extractos tirosinados de ácaros de polvo doméstico en pacientes con enfermedad alérgica Mónica María Molina-Sáenz Ana María Villa-Arango Ricardo Cardona-Villa Medicina Alergia Inmunoterapia Dermatophagoides Enfermedad respiratoria Antecedentes: Pese a los múltiples beneficios de la inmunoterapia alérgeno-específica, en algunos países se restringe su uso por temor a las reacciones adversas severas.Objetivo: Evaluar las reacciones sistémicas adversas en pacientes con dermatitis atópica, asma, rinitis y conjuntivitis alérgicas, que recibieron inmunoterapia subcutánea con extractos tirosinados para ácaros Dermatophagoides y Glycyphagoides.Métodos: Estudio retrospectivo del periodo 2010-2015 en el que se incluyó a 773 pacientes con diagnóstico de enfermedades mediadas por IgE. Se describió la seguridad de la inmunoterapia alérgeno-específica conforme al sistema de clasificación de las reacciones sistémicas con inmunoterapias subcutánea de la Organización Mundial de Alergias.Resultados: 79.7 % de los pacientes presentó rinitis, 54.9 % asma, 34.5 % conjuntivitis y 16.4 % dermatitis atópica. De 12 546 dosis subcutánea con extractos tirosinados se registraron 45 reacciones sistémicas: 12 grado 1 (30 %), 27 de grado 2 (67.5 %) y 1 grado 3 (2.5 %); la tasa de reacción fue de 0.35 por cada 100 inyecciones administradas, que representó una incidencia de 5.8 %. No se registraron reacciones fatales.Conclusión: Con la inmunoterapia subcutánea con extractos tirosinados de Dermatophagoides farinae, Dermatophagoides pteronyssinus y Blomia tropicalis se presentó una frecuencia de reacciones sistémicas similar a la informada con otros extractos. 2017 artículo científico 0002-5151 https://www.redalyc.org/articulo.oa?id=486755082007 https://www.redalyc.org/journal/4867/486755082007/ https://www.redalyc.org/journal/4867/486755082007/html/ https://www.redalyc.org/journal/4867/486755082007/486755082007.epub https://www.redalyc.org/journal/4867/486755082007/movil 10.29262/ram.v64i1.233 es http://www.redalyc.org/revista.oa?id=4867 Revista Alergia México application/pdf Colegio Mexicano de Inmunología Clínica y Alergia, A.C. Revista Alergia México (México) Num.1 Vol.64

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* * @return void */ public function writeClose() { // The assumption is that we're using PHP's ext/session. // session_write_close() will actually overwrite $_SESSION with an // empty array on completion -- which leads to a mismatch between what // is in the storage object and $_SESSION. To get around this, we // temporarily reset $_SESSION to an array, and then re-link it to // the storage object. // // Additionally, while you _can_ write to $_SESSION following a // session_write_close() operation, no changes made to it will be // flushed to the session handler. As such, we now mark the storage // object isImmutable. $storage = $this->getStorage(); if (! $storage->isImmutable()) { $_SESSION = $storage->toArray(true); session_write_close(); $storage->fromArray($_SESSION); $storage->markImmutable(); } } /** * Attempt to set the session name * * If the session has already been started, or if the name provided fails * validation, an exception will be raised. * * @param string $name * @return SessionManager * @throws Exception\InvalidArgumentException */ public function setName($name) { if ($this->sessionExists()) { throw new Exception\InvalidArgumentException( 'Cannot set session name after a session has already started'

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