Estimation of Salivary Malondialdehyde Levels in Smokeless Tobacco Chewers with Chronic Periodontitis-A Cross Sectional Clinico Biochemical Study
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| Natura: | Artículo científico |
| Lingua: | en |
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Universidad de Costa Rica
2021
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| _version_ | 1876431122342084608 |
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| author | Shivaraj B. Warad |
| author_facet | Shivaraj B. Warad |
| contents | Estimation of Salivary Malondialdehyde Levels in Smokeless Tobacco Chewers with Chronic Periodontitis-A Cross Sectional Clinico Biochemical Study Shivaraj B. Warad Jyoti Pattanashetti Nagaraj Kalburgi Arati Koregol Subramaniam Rao Medicina Periodontitis (CP) Malondialdehyde (MDA) Oxidative stress (OS) Lipid peroxidation (LPO) Thio barbituric acid reacting substances (TBARS) Despite the reported effects of smokeless tobacco (ST) on the periodontium and high prevalence of ST use in rural populations and in males studies on this specific topic are limited. The purpose of this cross-sectional investigation was to measure lipid peroxidation (as an end product of oxidative stress) end product i.e. Malondialdehyde (MDA) in saliva of patients with gingivitis, chronic periodontitis and to assess the influence of smokeless tobacco on Salivary Malondialdehyde (S-MDA). Total 30 patients with gingivitis, 30 with chronic periodontitis and 30 Smokeless Tobacco Chewers with Chronic Periodontitis and 30 periodontally healthy subjects were included in the study. Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PD), and Clinical Attachment Loss (CAL) were recorded followed by stimulated Saliva sample collection. Salivary MDA Levels were assessed by UV Spectrophotometry. There was a statistically significant increase in the salivary MDA levels in gingivitis, chronic periodontitis and in smokeless tobacco chewers with chronic periodontitis when compared with healthy group. Higher salivary MDA levels in gingivitis group, chronic periodontitis, and smokeless tobacco chewers with chronic periodontitis reflects increasedoxygen radical activity during periodontal inflammation. 2021 artículo científico 1659-1046 https://www.redalyc.org/articulo.oa?id=499569367015 https://www.redalyc.org/journal/4995/499569367015/ https://www.redalyc.org/journal/4995/499569367015/html/ https://www.redalyc.org/journal/4995/499569367015/499569367015.epub https://www.redalyc.org/journal/4995/499569367015/movil 10.15517/IJDS.2021.45930 en http://www.redalyc.org/revista.oa?id=4995 Odovtos - International Journal of Dental Sciences application/pdf Universidad de Costa Rica Odovtos - International Journal of Dental Sciences (Costa Rica) Num.3 Vol.23 |
| format | Artículo científico |
| id | redalyc_499569367015 |
| institution | Redalyc |
| language | en |
| publishDate | 2021 |
| publisher | Universidad de Costa Rica |
| spellingShingle | Estimation of Salivary Malondialdehyde Levels in Smokeless Tobacco Chewers with Chronic Periodontitis-A Cross Sectional Clinico Biochemical Study Shivaraj B. Warad Medicina Periodontitis (CP) Malondialdehyde (MDA) Oxidative stress (OS) Lipid peroxidation (LPO) Thio barbituric acid reacting substances (TBARS) Estimation of Salivary Malondialdehyde Levels in Smokeless Tobacco Chewers with Chronic Periodontitis-A Cross Sectional Clinico Biochemical Study Shivaraj B. Warad Jyoti Pattanashetti Nagaraj Kalburgi Arati Koregol Subramaniam Rao Medicina Periodontitis (CP) Malondialdehyde (MDA) Oxidative stress (OS) Lipid peroxidation (LPO) Thio barbituric acid reacting substances (TBARS) Despite the reported effects of smokeless tobacco (ST) on the periodontium and high prevalence of ST use in rural populations and in males studies on this specific topic are limited. The purpose of this cross-sectional investigation was to measure lipid peroxidation (as an end product of oxidative stress) end product i.e. Malondialdehyde (MDA) in saliva of patients with gingivitis, chronic periodontitis and to assess the influence of smokeless tobacco on Salivary Malondialdehyde (S-MDA). Total 30 patients with gingivitis, 30 with chronic periodontitis and 30 Smokeless Tobacco Chewers with Chronic Periodontitis and 30 periodontally healthy subjects were included in the study. Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PD), and Clinical Attachment Loss (CAL) were recorded followed by stimulated Saliva sample collection. Salivary MDA Levels were assessed by UV Spectrophotometry. There was a statistically significant increase in the salivary MDA levels in gingivitis, chronic periodontitis and in smokeless tobacco chewers with chronic periodontitis when compared with healthy group. Higher salivary MDA levels in gingivitis group, chronic periodontitis, and smokeless tobacco chewers with chronic periodontitis reflects increasedoxygen radical activity during periodontal inflammation. 2021 artículo científico 1659-1046 https://www.redalyc.org/articulo.oa?id=499569367015 https://www.redalyc.org/journal/4995/499569367015/ https://www.redalyc.org/journal/4995/499569367015/html/ https://www.redalyc.org/journal/4995/499569367015/499569367015.epub https://www.redalyc.org/journal/4995/499569367015/movil 10.15517/IJDS.2021.45930 en http://www.redalyc.org/revista.oa?id=4995 Odovtos - International Journal of Dental Sciences application/pdf Universidad de Costa Rica Odovtos - International Journal of Dental Sciences (Costa Rica) Num.3 Vol.23 |
| title | Estimation of Salivary Malondialdehyde Levels in Smokeless Tobacco Chewers with Chronic Periodontitis-A Cross Sectional Clinico Biochemical Study |
| topic | Medicina Periodontitis (CP) Malondialdehyde (MDA) Oxidative stress (OS) Lipid peroxidation (LPO) Thio barbituric acid reacting substances (TBARS) |
| url | https://www.redalyc.org/articulo.oa?id=499569367015 https://www.redalyc.org/journal/4995/499569367015/ https://www.redalyc.org/journal/4995/499569367015/html/ https://www.redalyc.org/journal/4995/499569367015/499569367015.epub https://www.redalyc.org/journal/4995/499569367015/movil |