Novel, broad-specrum antimycotic agents: the role of echinocandins today
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| Format: | Artículo científico |
| Language: | en |
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Sociedad Venezolana de Farmacología Clínica y Terapéutica
2010
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| _version_ | 1876430035794001920 |
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| author | Roberto Manfredi |
| author_facet | Roberto Manfredi |
| contents | Novel, broad-specrum antimycotic agents: the role of echinocandins today Roberto Manfredi Medicina micafungin caspofungin indications echinocandins anidulafungin The echinocandins show comparable effi cacy in the treatmentof candidemia and invasive candidiasis. Caspofungin and micafungin appear to be similarly effi cacious in salvagetherapy in aspergillosis; anidulafungin has excellent in vitro activity against Aspergillus species but as yet there are no sufficient clinical data for anidulafungin in this disease state.Each drug has minor advantages and disadvantages compared to the others of the same classe; however, there arelarge differences in the approved indications for the differentdrugs. The formulary selection process should consider the direct and indirect costs of the single agents; the characteristics of the patient population at risk for invasive mycosis,such as frequent use of interacting drugs and the burden ofmonitoring plasma drug levels of drugs; and the implications of using products for indications which have not been still approved (off-label indications) 2010 artículo científico 0798-0264 https://www.redalyc.org/articulo.oa?id=55916222002 en http://www.redalyc.org/revista.oa?id=559 Archivos Venezolanos de Farmacología y Terapéutica application/pdf Sociedad Venezolana de Farmacología Clínica y Terapéutica Archivos Venezolanos de Farmacología y Terapéutica (República Bolivariana de Venezuela) Num.3 Vol.29 |
| format | Artículo científico |
| id | redalyc_55916222002 |
| institution | Redalyc |
| language | en |
| publishDate | 2010 |
| publisher | Sociedad Venezolana de Farmacología Clínica y Terapéutica |
| spellingShingle | Novel, broad-specrum antimycotic agents: the role of echinocandins today Roberto Manfredi Medicina micafungin caspofungin indications echinocandins anidulafungin Novel, broad-specrum antimycotic agents: the role of echinocandins today Roberto Manfredi Medicina micafungin caspofungin indications echinocandins anidulafungin The echinocandins show comparable effi cacy in the treatmentof candidemia and invasive candidiasis. Caspofungin and micafungin appear to be similarly effi cacious in salvagetherapy in aspergillosis; anidulafungin has excellent in vitro activity against Aspergillus species but as yet there are no sufficient clinical data for anidulafungin in this disease state.Each drug has minor advantages and disadvantages compared to the others of the same classe; however, there arelarge differences in the approved indications for the differentdrugs. The formulary selection process should consider the direct and indirect costs of the single agents; the characteristics of the patient population at risk for invasive mycosis,such as frequent use of interacting drugs and the burden ofmonitoring plasma drug levels of drugs; and the implications of using products for indications which have not been still approved (off-label indications) 2010 artículo científico 0798-0264 https://www.redalyc.org/articulo.oa?id=55916222002 en http://www.redalyc.org/revista.oa?id=559 Archivos Venezolanos de Farmacología y Terapéutica application/pdf Sociedad Venezolana de Farmacología Clínica y Terapéutica Archivos Venezolanos de Farmacología y Terapéutica (República Bolivariana de Venezuela) Num.3 Vol.29 |
| title | Novel, broad-specrum antimycotic agents: the role of echinocandins today |
| topic | Medicina micafungin caspofungin indications echinocandins anidulafungin |
| url | https://www.redalyc.org/articulo.oa?id=55916222002 |