Pathology of the testicle after long-term anabolic steroid treatment in a thoroughbread horse from Venezuela

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Autor principal: Abelardo Morales Briceño
Formato: Artículo científico
Lenguaje:es
Publicado: Sociedad Venezolana de Farmacología Clínica y Terapéutica 2011
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author Abelardo Morales Briceño
author_facet Abelardo Morales Briceño
contents Pathology of the testicle after long-term anabolic steroid treatment in a thoroughbread horse from Venezuela Abelardo Morales Briceño Francisco García Mario Rossini Gerardo Campos Victor Bermúdez Medicina The aim of this study was to describe a case of pathology of the testicle after long-term anabolic steroid treatment in a Thoroughbread horse. Were study an equine Thoroughbread with cryptorchidism from Venezuela, male of 5 years old. With history of lameness chronic and subfertility. Necropsy was performed and samples of testicle tissue were collected. The tissue samples were fixed in formalin and processed by conventional H&E techniques. Additionally, the special staining procedure of Tricromico de Gomory and Blue VonKossa were also carried out. Samples of blood and urine were recollected for toxicological by competitive ELISA. The left testicle was diameter testicle 6cm. and cryptorchidism (testicle right). Macroscopic were observed bilateral fibrosis parenchyma testicle and atrophic. The histological study revealed atrophy of seminiferous tubules and interstitial fibrosis increases in collagen fibres in the lamina propria of seminiferous tubules and testicular interstitium. Lamina propria surrounding atrophic tubules was thickened by an increase in collagen type IV and elastic fibres and by proliferation of bizarre myoid cells. Basal lamina was also thickened but had decreased for collagen type IV. Special stain Tricromico de Gomory (+) showed fibrosis interstitium severed and VonKossa (-) no evidence mineral. Toxicological studies allowed the detection of boldenona and dexamethasone generic in blood and urine samples. To conclude, we detected the presence of pathology of the testicle associated a after long-term anabolic steroid treatment in a Thoroughbred horse. 2011 artículo científico 0798-0264 https://www.redalyc.org/articulo.oa?id=55919726005 es http://www.redalyc.org/revista.oa?id=559 Archivos Venezolanos de Farmacología y Terapéutica application/pdf Sociedad Venezolana de Farmacología Clínica y Terapéutica Archivos Venezolanos de Farmacología y Terapéutica (República Bolivariana de Venezuela) Num.3 Vol.30
format Artículo científico
id redalyc_55919726005
institution Redalyc
language es
publishDate 2011
publisher Sociedad Venezolana de Farmacología Clínica y Terapéutica
spellingShingle Pathology of the testicle after long-term anabolic steroid treatment in a thoroughbread horse from Venezuela
Abelardo Morales Briceño
Medicina
Pathology of the testicle after long-term anabolic steroid treatment in a thoroughbread horse from Venezuela Abelardo Morales Briceño Francisco García Mario Rossini Gerardo Campos Victor Bermúdez Medicina The aim of this study was to describe a case of pathology of the testicle after long-term anabolic steroid treatment in a Thoroughbread horse. Were study an equine Thoroughbread with cryptorchidism from Venezuela, male of 5 years old. With history of lameness chronic and subfertility. Necropsy was performed and samples of testicle tissue were collected. The tissue samples were fixed in formalin and processed by conventional H&E techniques. Additionally, the special staining procedure of Tricromico de Gomory and Blue VonKossa were also carried out. Samples of blood and urine were recollected for toxicological by competitive ELISA. The left testicle was diameter testicle 6cm. and cryptorchidism (testicle right). Macroscopic were observed bilateral fibrosis parenchyma testicle and atrophic. The histological study revealed atrophy of seminiferous tubules and interstitial fibrosis increases in collagen fibres in the lamina propria of seminiferous tubules and testicular interstitium. Lamina propria surrounding atrophic tubules was thickened by an increase in collagen type IV and elastic fibres and by proliferation of bizarre myoid cells. Basal lamina was also thickened but had decreased for collagen type IV. Special stain Tricromico de Gomory (+) showed fibrosis interstitium severed and VonKossa (-) no evidence mineral. Toxicological studies allowed the detection of boldenona and dexamethasone generic in blood and urine samples. To conclude, we detected the presence of pathology of the testicle associated a after long-term anabolic steroid treatment in a Thoroughbred horse. 2011 artículo científico 0798-0264 https://www.redalyc.org/articulo.oa?id=55919726005 es http://www.redalyc.org/revista.oa?id=559 Archivos Venezolanos de Farmacología y Terapéutica application/pdf Sociedad Venezolana de Farmacología Clínica y Terapéutica Archivos Venezolanos de Farmacología y Terapéutica (República Bolivariana de Venezuela) Num.3 Vol.30
title Pathology of the testicle after long-term anabolic steroid treatment in a thoroughbread horse from Venezuela
topic Medicina
url https://www.redalyc.org/articulo.oa?id=55919726005