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| Natura: | Artículo científico |
| Lingua: | en |
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Sociedad Venezolana de Farmacología Clínica y Terapéutica
2018
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| Accesso online: | https://www.redalyc.org/articulo.oa?id=55963209004 https://www.redalyc.org/journal/559/55963209004/ https://www.redalyc.org/journal/559/55963209004/html/ https://www.redalyc.org/journal/559/55963209004/55963209004.epub https://www.redalyc.org/journal/559/55963209004/movil |
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Sommario:
- Assessment of methods for volumetric quantification of intracerebral hematomas in computerized tomography images Miguel Vera Yoleidy Huérfano Doris Barrera Williams Salazar María Isabel Vera Carlos Hernández Maryury Borrero Ángel Valentín Molina Luis Javier Martínez Oscar Valbuena Juan Salazar Elkin Gelvez Yudith Contreras Marisela Vivas Frank Sáenz Medicina ABC Methods Segmentation Intelligent Automatic Technique Intracerebral Hematoma Volumetry This work evaluates the performance of computational methods aimed at volume generation of five intracerebral hematomas (ICH), present in multi-layer computed tomography images. First one, a ground truth volume or reference volume (RV) is considered. This RV is obtained, by a neurosurgeon, using the manual planimetric method (MPM), which allows the generation of manual segmentations of space-occupying injuries which, in this case, are matched with the ICH. The MPM consists in: a) Manually drawing the contour that delimits the ICH, in each of the layers or cuts in which the ICH is present b) Calculate the partial area using the number of pixels contained in each contour c) Obtain the total area of the ICH by adding the partial areas d) Calculate the volume considering the total number of layers, the total area of the ICH and the thickness of each layer. In second place, the volumetry of the 5 ICH’s is obtained considering both the original version of the ABC/2 method and two of its variants, identified in this paper as ABC/3 method and 2ABC/3 method. The ABC methods allow for calculating hematoma volume under the geometric assumption that the ICH has an ellipsoidal shape. In these methods, A is the maximum diameter of the ICH, B is the length of the ICH measured, perpendicularly, with respect to the parameter A; while C represents the product of the thickness of the cut by the number of cuts in which the ICH is present. In third place, a smart automatic technique (SAT) is implemented to generate the three-dimensional segmentation of each ICH and from it the volume of the hematoma is calculated by multiplying the voxel dimensions by the number of voxels that make up the ICH. In the context of the present work, the expression SAT method will be used to refer to the new methodology that is proposed to calculate the volume of the ICH. The SAT consists of the pre-processing, segmentation and post-processing stages. During pre-processing, a thresholding algorithm and a bank of computational filters are used to address artifact and image noise problems. In segmentation, the growth of regions is applied to pre-processed images. Finally, a morphological dilation filter is used as a technique to perform the post-processing of the segmented images. In order to make judgments about the performance of the SAT, the Dice coefficient (Dc) is used to compare the dilated segmentations of the ICH with the ICH segmentations generated, manually, by a neurosurgeon. The combination of parameters linked to the highest Dc, allows to establish the optimal parameters of each of the computational algorithms that make up the SAT. Finally, the percentage relative error is calculated as a metric to evaluate the methodologies considered. The results show that the SAT method exhibits the best performance, generating an average percentage error of less than 3%. 2018 artículo científico 0798-0264 https://www.redalyc.org/articulo.oa?id=55963209004 https://www.redalyc.org/journal/559/55963209004/ https://www.redalyc.org/journal/559/55963209004/html/ https://www.redalyc.org/journal/559/55963209004/55963209004.epub https://www.redalyc.org/journal/559/55963209004/movil en http://www.redalyc.org/revista.oa?id=559 Archivos Venezolanos de Farmacología y Terapéutica application/pdf Sociedad Venezolana de Farmacología Clínica y Terapéutica Archivos Venezolanos de Farmacología y Terapéutica (República Bolivariana de Venezuela) Num.4 Vol.37