Comprehensive assessment of the carcinogenic risk to adolescent health of chemicals
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| Format: | Artículo científico |
| Sprache: | en |
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Sociedad Venezolana de Farmacología Clínica y Terapéutica
2020
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| _version_ | 1876428219322728448 |
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| author | Valeeva Emiliya Ramzievna |
| author_facet | Valeeva Emiliya Ramzievna |
| contents | Comprehensive assessment of the carcinogenic risk to adolescent health of chemicals Valeeva Emiliya Ramzievna Ismagilova G.A. Stepanova N.V Ziyatdinova A.I Medicina Comprehensive assessment of carcinogenic risk in adolescents The value of total carcinogenic risk on peroral, inhalation and dermal routes of entry for the adolescent population in all zones under study corresponded to high risk level, the highest values being observed in the 1st zone (the Kirovsky district), and the lowest ones in the 4th zone (the Privolzhsky district). The priority routes of carcinogen entry into the human body were peroral and inhalation routes. Foods and drinking water, as well as atmospheric air were revealed to be the leading substance transport media in forming individual carcinogenic risk. The major carcinogens forming risk were lead (1.36Е-04), chloroform (1.20Е-04) and cadmium (7.09E-04) entering with water and arsenic (8.38Е-05) – with soil. The leading position among atmospheric air carcinogens in all city zones under study belonged to soot (5.51Е-04). The priority pollutant present in foods and defining carcinogenic health risk was lead (2.02E-03). Complex assessment of carcinogenic risk in case of multimedium routes of the chemicals’ entry showed that there was a risk of developing carcinogenic effects for the adolescents’ health on daily intake of contaminants, which made TНCR=0.01632. 2020 artículo científico 0798-0264 https://www.redalyc.org/articulo.oa?id=55965388014 https://www.redalyc.org/journal/559/55965388014/ https://www.redalyc.org/journal/559/55965388014/html/ https://www.redalyc.org/journal/559/55965388014/55965388014.epub https://www.redalyc.org/journal/559/55965388014/movil https://doi.org/10.5281/zenodo.4425066 en http://www.redalyc.org/revista.oa?id=559 Archivos Venezolanos de Farmacología y Terapéutica application/pdf Sociedad Venezolana de Farmacología Clínica y Terapéutica Archivos Venezolanos de Farmacología y Terapéutica (República Bolivariana de Venezuela) Num.7 Vol.39 |
| format | Artículo científico |
| id | redalyc_55965388014 |
| institution | Redalyc |
| language | en |
| publishDate | 2020 |
| publisher | Sociedad Venezolana de Farmacología Clínica y Terapéutica |
| spellingShingle | Comprehensive assessment of the carcinogenic risk to adolescent health of chemicals Valeeva Emiliya Ramzievna Medicina Comprehensive assessment of carcinogenic risk in adolescents Comprehensive assessment of the carcinogenic risk to adolescent health of chemicals Valeeva Emiliya Ramzievna Ismagilova G.A. Stepanova N.V Ziyatdinova A.I Medicina Comprehensive assessment of carcinogenic risk in adolescents The value of total carcinogenic risk on peroral, inhalation and dermal routes of entry for the adolescent population in all zones under study corresponded to high risk level, the highest values being observed in the 1st zone (the Kirovsky district), and the lowest ones in the 4th zone (the Privolzhsky district). The priority routes of carcinogen entry into the human body were peroral and inhalation routes. Foods and drinking water, as well as atmospheric air were revealed to be the leading substance transport media in forming individual carcinogenic risk. The major carcinogens forming risk were lead (1.36Е-04), chloroform (1.20Е-04) and cadmium (7.09E-04) entering with water and arsenic (8.38Е-05) – with soil. The leading position among atmospheric air carcinogens in all city zones under study belonged to soot (5.51Е-04). The priority pollutant present in foods and defining carcinogenic health risk was lead (2.02E-03). Complex assessment of carcinogenic risk in case of multimedium routes of the chemicals’ entry showed that there was a risk of developing carcinogenic effects for the adolescents’ health on daily intake of contaminants, which made TНCR=0.01632. 2020 artículo científico 0798-0264 https://www.redalyc.org/articulo.oa?id=55965388014 https://www.redalyc.org/journal/559/55965388014/ https://www.redalyc.org/journal/559/55965388014/html/ https://www.redalyc.org/journal/559/55965388014/55965388014.epub https://www.redalyc.org/journal/559/55965388014/movil https://doi.org/10.5281/zenodo.4425066 en http://www.redalyc.org/revista.oa?id=559 Archivos Venezolanos de Farmacología y Terapéutica application/pdf Sociedad Venezolana de Farmacología Clínica y Terapéutica Archivos Venezolanos de Farmacología y Terapéutica (República Bolivariana de Venezuela) Num.7 Vol.39 |
| title | Comprehensive assessment of the carcinogenic risk to adolescent health of chemicals |
| topic | Medicina Comprehensive assessment of carcinogenic risk in adolescents |
| url | https://www.redalyc.org/articulo.oa?id=55965388014 https://www.redalyc.org/journal/559/55965388014/ https://www.redalyc.org/journal/559/55965388014/html/ https://www.redalyc.org/journal/559/55965388014/55965388014.epub https://www.redalyc.org/journal/559/55965388014/movil https://doi.org/10.5281/zenodo.4425066 |