Cyclooxygenase biology in renal function - literature review
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| Natura: | Artículo científico |
| Lingua: | en |
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Asociación Colombiana de Nefrología e Hipertensión Arterial
2017
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| _version_ | 1876423678602772480 |
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| author | Marcella Goetz Moro |
| author_facet | Marcella Goetz Moro |
| contents | Cyclooxygenase biology in renal function - literature review Marcella Goetz Moro Paula Katherine Vargas Sánchez Ana Caroline Lupepsa Emeline Maria Baller Gilson César Nobre Franco Medicina Anti Kidney Biology Pathology Cyclooxygenase 1 The cyclooxygenase (COX) exists in two main isoforms, COX-1 and COX-2, which are present in the renal system to ensure its homeostasis. However, in different clinical situations, these enzymes can play a physiologic role in maintaining the integrity of this organ, and also be associated with the worsening of tissue injuries/damage. In this sense, an explanation of the true biological function of the isoforms of COX enables a better understanding of the physiology and pathology of the kidney, as well as a better understanding of the consequences of its inhibition by the use of drugs. This review aimed to study the biological role of the COX enzyme in the renal system in different clinical situations. 2017 reseña 2389-7708 https://www.redalyc.org/articulo.oa?id=560159495003 https://www.redalyc.org/journal/5601/560159495003/ https://www.redalyc.org/journal/5601/560159495003/html/ https://www.redalyc.org/journal/5601/560159495003/560159495003.epub https://www.redalyc.org/journal/5601/560159495003/movil 10.22265/acnef.4.1.263 en http://www.redalyc.org/revista.oa?id=5601 Revista Colombiana de Nefrología application/pdf Asociación Colombiana de Nefrología e Hipertensión Arterial Revista Colombiana de Nefrología (Colombia) Num.1 Vol.4 |
| format | Artículo científico |
| id | redalyc_560159495003 |
| institution | Redalyc |
| language | en |
| publishDate | 2017 |
| publisher | Asociación Colombiana de Nefrología e Hipertensión Arterial |
| spellingShingle | Cyclooxygenase biology in renal function - literature review Marcella Goetz Moro Medicina Anti Kidney Biology Pathology Cyclooxygenase 1 Cyclooxygenase biology in renal function - literature review Marcella Goetz Moro Paula Katherine Vargas Sánchez Ana Caroline Lupepsa Emeline Maria Baller Gilson César Nobre Franco Medicina Anti Kidney Biology Pathology Cyclooxygenase 1 The cyclooxygenase (COX) exists in two main isoforms, COX-1 and COX-2, which are present in the renal system to ensure its homeostasis. However, in different clinical situations, these enzymes can play a physiologic role in maintaining the integrity of this organ, and also be associated with the worsening of tissue injuries/damage. In this sense, an explanation of the true biological function of the isoforms of COX enables a better understanding of the physiology and pathology of the kidney, as well as a better understanding of the consequences of its inhibition by the use of drugs. This review aimed to study the biological role of the COX enzyme in the renal system in different clinical situations. 2017 reseña 2389-7708 https://www.redalyc.org/articulo.oa?id=560159495003 https://www.redalyc.org/journal/5601/560159495003/ https://www.redalyc.org/journal/5601/560159495003/html/ https://www.redalyc.org/journal/5601/560159495003/560159495003.epub https://www.redalyc.org/journal/5601/560159495003/movil 10.22265/acnef.4.1.263 en http://www.redalyc.org/revista.oa?id=5601 Revista Colombiana de Nefrología application/pdf Asociación Colombiana de Nefrología e Hipertensión Arterial Revista Colombiana de Nefrología (Colombia) Num.1 Vol.4 |
| title | Cyclooxygenase biology in renal function - literature review |
| topic | Medicina Anti Kidney Biology Pathology Cyclooxygenase 1 |
| url | https://www.redalyc.org/articulo.oa?id=560159495003 https://www.redalyc.org/journal/5601/560159495003/ https://www.redalyc.org/journal/5601/560159495003/html/ https://www.redalyc.org/journal/5601/560159495003/560159495003.epub https://www.redalyc.org/journal/5601/560159495003/movil |