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| Format: | Artículo científico |
| Language: | en |
| Published: |
Universidad del Rosario
2017
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| Online Access: | https://www.redalyc.org/articulo.oa?id=56249528010 https://www.redalyc.org/journal/562/56249528010/ https://www.redalyc.org/journal/562/56249528010/html/ https://www.redalyc.org/journal/562/56249528010/56249528010.epub https://www.redalyc.org/journal/562/56249528010/movil |
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Table of Contents:
- Environmental Risk Factors and Acute Lymphoblastic Leukaemia in Childhood Fernanda Alves Cangerana Pereira Antônio Pedro Mirra Maria do Rosário Dias de Oliveira Latorre João Vicente de Assunção Salud Leukemia childhood environmental factors Objectives: To verify the paper of environmental risks in the process of developing Acute lym - phoblastic leukemia ( all ) in childhood. Materials and methods: A search was conducted on sci - entific literature in order to evaluate the role of environmental risk factors in acute lymphoblastic leukemia development. Results: The environmental role in development of all in children is unknown. The two steps theory proposed by Greaves in 1988 is the most acceptable hypothesis. One first event occurs in uterus or near the moment of birth; this mutation induces the devel - opment of pre-leukemia clones. Another event, happening in the early infancy, would develop this first pre-leukemia clone into clinical leukemia. Based on the environmental events linked to other types of leukemia and in other studies, some risk factors have been proposed as inducing the mutations leading to all . Radiation (ionizing or not), infectious agents, and chemical prod - ucts are thought to be the responsible for the disease. In the last decades, many authors tried to found an association between these risk factors and the development of childhood all . The results however were inconclusive and even contradictories. Ionizing radiation is the only one proved to play a role in the development of leukemia. Conclusion: As leukemia is a disease that affects children, costs of this pathology are high when talking about money expend for diagnosis and treatment and when thinking on the social and psychological burden. 2017 artículo científico 1692-7273 https://www.redalyc.org/articulo.oa?id=56249528010 https://www.redalyc.org/journal/562/56249528010/ https://www.redalyc.org/journal/562/56249528010/html/ https://www.redalyc.org/journal/562/56249528010/56249528010.epub https://www.redalyc.org/journal/562/56249528010/movil en http://www.redalyc.org/revista.oa?id=562 Revista Ciencias de la Salud application/pdf Universidad del Rosario Revista Ciencias de la Salud (Colombia) Num.1 Vol.15