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Bibliographic Details
Main Author:	Mercedes Guadalupe Espin
Format:	Artículo científico
Language:	es
Published:	Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires 2018
Subjects:	Medicina lesiones hemodiálisis diálisis renal diabetes mellitus Dermatosis perforante adquirida
Online Access:	https://www.redalyc.org/articulo.oa?id=564262467010 https://www.redalyc.org/journal/5642/564262467010/ https://www.redalyc.org/journal/5642/564262467010/html/ https://www.redalyc.org/journal/5642/564262467010/564262467010.epub https://www.redalyc.org/journal/5642/564262467010/movil
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Dermatosis perforante adquirida. Reporte de dos casos en pacientes con diabetes mellitus y enfermedad renal crónica en hemodiálisis Mercedes Guadalupe Espin Cintia Verónica Marín María del Pilar Beruchi Rosana Lago Fernando Segovia Matías Abuchanab Medicina lesiones hemodiálisis diálisis renal diabetes mellitus Dermatosis perforante adquirida Las dermatosis perforantes (DP), constituyen un grupo heterogéneo de enfermedades hereditarias o adquiridas caracterizadas por la migración transepidérmica de componentes de la matriz extracelular de la dermis (colágeno, tejido elástico o tejido conectivo necrótico) luego de un proceso inflamatorio y/o degenerativo. La etiopatogenia de la dermatosis perforante adquirida (DPA) es desconocida. Sin embargo presenta una fuerte asociación con traumatismos leves, insuficiencia renal crónica (IRC) y diabetes mellitus, y con menor frecuencia, con endocrinopatías, enfermedades infectocontagiosas y neoplasias, entre otras. En pacientes que realizan hemodiálisis, las DPA pueden observarse en el 10 al 12% de los casos. El prurito es el síntoma cardinal de esta entidad. En algunos pacientes su intensidad puede incluso llegar a ser discapacitante, y las excoriaciones por rascado secundarias al mismo llegan a generar extensas lesiones con alteración de la función de la piel como barrera cutánea. Se presentan dos casos clínicos, ambos con antecedentes de diabetes mellitus e IRC en etapa terminal, con requerimiento de terapia de reemplazo renal (TRR), en hemodiálisis trisemanal. Consultan por una dermatosis pruriginosa generalizada de meses de evolución. Al examen físico presentan lesiones sobreelevadas, hiperpigmentadas, con centro umbilicado rodeadas por un halo eritematoso, localizadas en rostro, tronco y miembros. El examen histopatológico revela una DPA. 2018 artículo científico 0326-3428 https://www.redalyc.org/articulo.oa?id=564262467010 https://www.redalyc.org/journal/5642/564262467010/ https://www.redalyc.org/journal/5642/564262467010/html/ https://www.redalyc.org/journal/5642/564262467010/564262467010.epub https://www.redalyc.org/journal/5642/564262467010/movil es http://www.redalyc.org/revista.oa?id=5642 Revista de nefrología, diálisis y transplante application/pdf Asociación Regional de Diálisis y Trasplantes Renales de Capital Federal y Provincia de Buenos Aires Revista de nefrología, diálisis y transplante (Argentina) Num.3 Vol.38

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