Prevalence of bacterial infections and antimicrobial resistance profile in hospitalized patients with COVID-19
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| Format: | Artículo científico |
| Language: | en |
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Universidade de Santa Cruz do Sul
2024
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| _version_ | 1876470986579116032 |
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| author | Jhully Pimentel |
| author_facet | Jhully Pimentel |
| contents | Prevalence of bacterial infections and antimicrobial resistance profile in hospitalized patients with COVID-19 Jhully Pimentel Thayglerson Augusto Almeida Paixão Ana Helena Croce Évelyn Faria Zanni Thaís Dias Lemos Kaiser Salud 19 COVID Microbial Drug Resistance Cross Infection Background and Objectives: bacterial resistance is an important public health problem worldwide and is related to the indiscriminate use of antimicrobials, limiting the available therapeutic options. The COVID-19 pandemic aggravated this scenario, since the lack of a standardized therapy led to a considerable increase in the prescription of these drugs. Therefore, we proposed to investigate the prevalence of bacterial infections and the profile of antimicrobial resistance in patients diagnosed with COVID-19 as well as to point out possible risk factors. Methods: a retrospective study based on the analysis of medical records of patients hospitalized with COVID-19 over the age of 18. Information such as age, gender, length of stay, hospitalization unit, bacterial species and resistance profile and previous use of antimicrobials by patients diagnosed with COVID-19 were collected and analyzed using Excel® 2016. Results: of the 268 patients with COVID-19, 162 had suspected bacterial infections, and 26 patients (9.7%) were confirmed from positive cultures. Furthermore, around 80% of these patients underwent empirical treatment with antimicrobials, the majority of whom were male and admitted to the Intensive Care Unit. A total of 32 bacterial isolates were recovered, of which 59.4% were resistant to at least one class of antimicrobials, with 21.8% being multidrug resistant. Conclusion: despite the low percentage found of patients with COVID-19 who had bacterial infections and of these 21.8% were by multidrug-resistant bacteria, the reinforcement in infection prevention policies and the adequate management in the release of antimicrobials is necessary to reduce the hospital dissemination rates of such bacteria. 2024 artículo científico 2238-3360 https://www.redalyc.org/articulo.oa?id=570477720006 https://www.redalyc.org/journal/5704/570477720006/ https://www.redalyc.org/journal/5704/570477720006/html/ https://www.redalyc.org/journal/5704/570477720006/570477720006.epub https://www.redalyc.org/journal/5704/570477720006/movil 10.17058/reci.v14i1.18336 en http://www.redalyc.org/revista.oa?id=5704 Revista de Epidemiologia e Controle de Infecção application/pdf Universidade de Santa Cruz do Sul Revista de Epidemiologia e Controle de Infecção (Brasil) Num.1 Vol.14 |
| format | Artículo científico |
| id | redalyc_570477720006 |
| institution | Redalyc |
| language | en |
| publishDate | 2024 |
| publisher | Universidade de Santa Cruz do Sul |
| spellingShingle | Prevalence of bacterial infections and antimicrobial resistance profile in hospitalized patients with COVID-19 Jhully Pimentel Salud 19 COVID Microbial Drug Resistance Cross Infection Prevalence of bacterial infections and antimicrobial resistance profile in hospitalized patients with COVID-19 Jhully Pimentel Thayglerson Augusto Almeida Paixão Ana Helena Croce Évelyn Faria Zanni Thaís Dias Lemos Kaiser Salud 19 COVID Microbial Drug Resistance Cross Infection Background and Objectives: bacterial resistance is an important public health problem worldwide and is related to the indiscriminate use of antimicrobials, limiting the available therapeutic options. The COVID-19 pandemic aggravated this scenario, since the lack of a standardized therapy led to a considerable increase in the prescription of these drugs. Therefore, we proposed to investigate the prevalence of bacterial infections and the profile of antimicrobial resistance in patients diagnosed with COVID-19 as well as to point out possible risk factors. Methods: a retrospective study based on the analysis of medical records of patients hospitalized with COVID-19 over the age of 18. Information such as age, gender, length of stay, hospitalization unit, bacterial species and resistance profile and previous use of antimicrobials by patients diagnosed with COVID-19 were collected and analyzed using Excel® 2016. Results: of the 268 patients with COVID-19, 162 had suspected bacterial infections, and 26 patients (9.7%) were confirmed from positive cultures. Furthermore, around 80% of these patients underwent empirical treatment with antimicrobials, the majority of whom were male and admitted to the Intensive Care Unit. A total of 32 bacterial isolates were recovered, of which 59.4% were resistant to at least one class of antimicrobials, with 21.8% being multidrug resistant. Conclusion: despite the low percentage found of patients with COVID-19 who had bacterial infections and of these 21.8% were by multidrug-resistant bacteria, the reinforcement in infection prevention policies and the adequate management in the release of antimicrobials is necessary to reduce the hospital dissemination rates of such bacteria. 2024 artículo científico 2238-3360 https://www.redalyc.org/articulo.oa?id=570477720006 https://www.redalyc.org/journal/5704/570477720006/ https://www.redalyc.org/journal/5704/570477720006/html/ https://www.redalyc.org/journal/5704/570477720006/570477720006.epub https://www.redalyc.org/journal/5704/570477720006/movil 10.17058/reci.v14i1.18336 en http://www.redalyc.org/revista.oa?id=5704 Revista de Epidemiologia e Controle de Infecção application/pdf Universidade de Santa Cruz do Sul Revista de Epidemiologia e Controle de Infecção (Brasil) Num.1 Vol.14 |
| title | Prevalence of bacterial infections and antimicrobial resistance profile in hospitalized patients with COVID-19 |
| topic | Salud 19 COVID Microbial Drug Resistance Cross Infection |
| url | https://www.redalyc.org/articulo.oa?id=570477720006 https://www.redalyc.org/journal/5704/570477720006/ https://www.redalyc.org/journal/5704/570477720006/html/ https://www.redalyc.org/journal/5704/570477720006/570477720006.epub https://www.redalyc.org/journal/5704/570477720006/movil |