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| Format: | Artículo científico |
| Language: | en |
| Published: |
Sociedad Mexicana de Física A.C.
2004
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| Online Access: | https://www.redalyc.org/articulo.oa?id=57050607 |
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| _version_ | 1866558319842295808 |
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| author | L. Dagdug |
| author_facet | L. Dagdug |
| contents | Theoretical basis for the study of the effect of base composition on DNA melting L. Dagdug L. Young Física, Astronomía y Matemáticas DNA melting temperature stochastic matrix method We extend the ideas used to describe the glass transition in strong glasses employing the stochastic matrix method, giving a theoreticalframework for the study of the configurational changes and the melting temperature of DNA. Our theoretical model enables a systematicstudy of the melting transition and the melting temperature dependence on the sequence differences in vertical stacking. Taking into accountthe fractional composition in a single strand, exact analytic results are given for the fraction of bonds intact and denatured at a particulartemperature. This method is applicable to long DNA as well as RNA. 2004 artículo científico 0035-001X https://www.redalyc.org/articulo.oa?id=57050607 en http://www.redalyc.org/revista.oa?id=570 Revista Mexicana de Física application/pdf Sociedad Mexicana de Física A.C. Revista Mexicana de Física (México) Num.Re6 Vol.50 |
| format | Artículo científico |
| id | redalyc_57050607 |
| language | en |
| publishDate | 2004 |
| publisher | Sociedad Mexicana de Física A.C. |
| spellingShingle | Theoretical basis for the study of the effect of base composition on DNA melting L. Dagdug Física, Astronomía y Matemáticas DNA melting temperature stochastic matrix method Theoretical basis for the study of the effect of base composition on DNA melting L. Dagdug L. Young Física, Astronomía y Matemáticas DNA melting temperature stochastic matrix method We extend the ideas used to describe the glass transition in strong glasses employing the stochastic matrix method, giving a theoreticalframework for the study of the configurational changes and the melting temperature of DNA. Our theoretical model enables a systematicstudy of the melting transition and the melting temperature dependence on the sequence differences in vertical stacking. Taking into accountthe fractional composition in a single strand, exact analytic results are given for the fraction of bonds intact and denatured at a particulartemperature. This method is applicable to long DNA as well as RNA. 2004 artículo científico 0035-001X https://www.redalyc.org/articulo.oa?id=57050607 en http://www.redalyc.org/revista.oa?id=570 Revista Mexicana de Física application/pdf Sociedad Mexicana de Física A.C. Revista Mexicana de Física (México) Num.Re6 Vol.50 |
| title | Theoretical basis for the study of the effect of base composition on DNA melting |
| topic | Física, Astronomía y Matemáticas DNA melting temperature stochastic matrix method |
| url | https://www.redalyc.org/articulo.oa?id=57050607 |