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| Natura: | Artículo científico |
| Lingua: | en |
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Hospital Universitário da Universidade de São Paulo
2020
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| Accesso online: | https://www.redalyc.org/articulo.oa?id=576065838015 https://www.redalyc.org/journal/5760/576065838015/ https://www.redalyc.org/journal/5760/576065838015/html/ https://www.redalyc.org/journal/5760/576065838015/576065838015.epub https://www.redalyc.org/journal/5760/576065838015/movil |
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Sommario:
- Coronavirus 229E with Rhinovirus co-infection causing severe acute respiratory distress syndrome with thrombotic microangiopathy and death during Covid-19 pandemic: lessons to be learnt Hubert Daisley Arlene Rampersad Martina Daisley Amit Ramdin Oneka Acco Medicina Adult Rhinovirus SARS virus Coronavirus infections Thrombotic Microangiopathies We report on a 3-month old infant male who had a seven-days history of fever and rhinorrhea associated with wheezing prior to his death, during the Covid-19 pandemic. Viral testing for Covid-19 (SARS-CoV-2) was negative but was positive for Coronavirus 229E and RP Human Rhinovirus. The pulmonary histological examination showed diffuse alveolar damage along with thrombotic microangiopathy affecting alveolar capillaries. Also, thrombotic microangiopathy was evident in the heart, lungs, brain, kidneys and liver. Thrombotic microangiopathy is a major pathologic finding in Acute Respiratory Distress Syndrome and in the multiorgan failure. This is the first report that illustrates thrombotic microangiopathy occurring in lung, heart, liver, kidney and brain in Acute Respiratory Distress Syndrome with Coronavirus 229E with Rhinovirus co-infection. The clinical presentation and pathological findings in our case share common features with Covid-19. 2020 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576065838015 https://www.redalyc.org/journal/5760/576065838015/ https://www.redalyc.org/journal/5760/576065838015/html/ https://www.redalyc.org/journal/5760/576065838015/576065838015.epub https://www.redalyc.org/journal/5760/576065838015/movil 10.4322/acr.2020.194 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Num.3 Vol.10