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| Auteur principal: | |
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| Format: | Artículo científico |
| Langue: | en |
| Publié: |
Hospital Universitário da Universidade de São Paulo
2021
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| Accès en ligne: | https://www.redalyc.org/articulo.oa?id=576067146123 https://www.redalyc.org/journal/5760/576067146123/ https://www.redalyc.org/journal/5760/576067146123/html/ https://www.redalyc.org/journal/5760/576067146123/576067146123.epub https://www.redalyc.org/journal/5760/576067146123/movil |
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Table des matières:
- Myeloid sarcoma: an uncommon presentation of myeloid neoplasms; a case series of 4 rare cases reported in a tertiary care institute Toyaja Jadhav Puneet Baveja Arijit Sen Medicina BCR Acute Sarcoma Myeloid Chronic Myeloid sarcoma (MS) is a rare extramedullary neoplasm of myeloid cells, which can arise before, concurrently with, or following hematolymphoid malignancies. We report 04 such cases of MS, diagnosed in this institute over a period of 6 years, during various phases of their respective myeloid neoplasms/leukemias. These cases include MS occurring as a relapse of AML (Case 1), MS occurring as an initial presentation of CML (Case 2), MS occurring during ongoing chemotherapy in APML (Case 3), and MS presenting as a progression of MDS to AML (Case 4). In the absence of relevant clinical history and unemployment of appropriate immunohistochemical (IHC) studies, these cases have a high risk of being frequently misdiagnosed either as Non-Hodgkin’s Lymphoma (NHL) or small round cell tumors or undifferentiated carcinomas, which may further delay their management, making an already bad prognosis worse. This case series has been designed to throw light on the varied presentation of MS and the lineage differentiation of its neoplastic cells through the application of relevant IHC markers along with their clinical correlation. 2021 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576067146123 https://www.redalyc.org/journal/5760/576067146123/ https://www.redalyc.org/journal/5760/576067146123/html/ https://www.redalyc.org/journal/5760/576067146123/576067146123.epub https://www.redalyc.org/journal/5760/576067146123/movil 10.4322/acr.2021.339 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.11