Saved in:
| Main Author: | |
|---|---|
| Format: | Artículo científico |
| Language: | en |
| Published: |
Hospital Universitário da Universidade de São Paulo
2022
|
| Subjects: | |
| Online Access: | https://www.redalyc.org/articulo.oa?id=576069818062 https://www.redalyc.org/journal/5760/576069818062/ https://www.redalyc.org/journal/5760/576069818062/html/ https://www.redalyc.org/journal/5760/576069818062/576069818062.epub https://www.redalyc.org/journal/5760/576069818062/movil |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Table of Contents:
- Adult-onset Still's disease after ChAdOx1 nCoV-19 vaccine: a possible association Laíssa Fiorotti Albertino Isac Ribeiro Moulaz Tammer Ferreira Zogheib Martina Zanotti Carneiro Valentim Ketty Lysie Libardi Lira Machado Medicina COVID Onset Adult 19 Vaccines Still's Disease With emergent Sars-Cov-2, a highly transmissive virus that caused millions of deaths worldwide, the development of vaccines became urgent to combat COVID-19. Although rare, important adverse effects had been described in a hypothetical scenario of immune system overstimulation or overreaction. Still’s disease is a rare inflammatory syndrome of unknown etiology. It manifests as a cytokine storm, mainly IL-18 and IL-1β, and presents itself with fever spikes, joint pain, maculopapular evanescent salmon-pink skin rash, and sore throat, among other symptoms. Here, we report a case of a 44-year-old healthy male who developed adult-onset Still’s disease (AOSD) with atypical symptoms after both doses of ChAdOx1 nCoV-19 vaccine with 3 months of dose interval. The medical team suspected Still's disease and started prednisone 1 mg/kg (40mg). The next day the patient showed a marked improvement in articular and chest pains and had no other fever episodes. Therefore, he was discharged to continue the treatment in outpatient care. On the six-month follow-up, the patient was free of complaints, and the progressive corticoid withdrawal plan was already finished. 2022 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576069818062 https://www.redalyc.org/journal/5760/576069818062/ https://www.redalyc.org/journal/5760/576069818062/html/ https://www.redalyc.org/journal/5760/576069818062/576069818062.epub https://www.redalyc.org/journal/5760/576069818062/movil 10.4322/acr.2021.403 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.12