Solitary fibrous tumor of the tongue
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| Format: | Artículo científico |
| Langue: | en |
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Hospital Universitário da Universidade de São Paulo
2022
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| _version_ | 1876450734864596992 |
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| author | Juliana Mota Siqueira |
| author_facet | Juliana Mota Siqueira |
| contents | Solitary fibrous tumor of the tongue Juliana Mota Siqueira Daniele Heguedusch Emília Maria Gomes Aguiar Anaeliza Figueiredo dos Santos Fabio Abreu Alves Fabio Daumas Nunes Medicina Oral diagnosis Oral Pathology Solitary Fibrous Tumors Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with a rare presentation in the oral cavity. Herein, we report a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination revealed a well-circumscribed mass covered by normal mucosa with a fibrous consistency. Due to non-specific clinical findings, the initial diagnostic hypotheses include benign submucosal neoplasms such as leiomyoma, neurofibroma, SFT, and others. An excisional biopsy was performed. Microscopically, the tumor was surrounded by a thick fibrous capsule; hypo and hypercellular areas were arranged in a storiform pattern with a stroma formed by collagen and abundant vascularization. Tumor cells showed immunopositivity for CD34 and STAT-6 and no expression of CD99, AML, S-100, and Ki-67. According to these findings, the diagnosis of SFT was established. After 24 months, the patient is asymptomatic and has no evidence of recurrence. Although oral involvement is rare, SFT should be included in the differential diagnosis of oral submucosal lesions. 2022 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576069818063 https://www.redalyc.org/journal/5760/576069818063/ https://www.redalyc.org/journal/5760/576069818063/html/ https://www.redalyc.org/journal/5760/576069818063/576069818063.epub https://www.redalyc.org/journal/5760/576069818063/movil 10.4322/acr.2021.405 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.12 |
| format | Artículo científico |
| id | redalyc_576069818063 |
| institution | Redalyc |
| language | en |
| publishDate | 2022 |
| publisher | Hospital Universitário da Universidade de São Paulo |
| spellingShingle | Solitary fibrous tumor of the tongue Juliana Mota Siqueira Medicina Oral diagnosis Oral Pathology Solitary Fibrous Tumors Solitary fibrous tumor of the tongue Juliana Mota Siqueira Daniele Heguedusch Emília Maria Gomes Aguiar Anaeliza Figueiredo dos Santos Fabio Abreu Alves Fabio Daumas Nunes Medicina Oral diagnosis Oral Pathology Solitary Fibrous Tumors Solitary fibrous tumor (SFT) is a benign mesenchymal neoplasm originally described in pleura with a rare presentation in the oral cavity. Herein, we report a case of a 28-year-old male patient who presented an asymptomatic slow-growing mass in the anterior part of the tongue. Intraoral examination revealed a well-circumscribed mass covered by normal mucosa with a fibrous consistency. Due to non-specific clinical findings, the initial diagnostic hypotheses include benign submucosal neoplasms such as leiomyoma, neurofibroma, SFT, and others. An excisional biopsy was performed. Microscopically, the tumor was surrounded by a thick fibrous capsule; hypo and hypercellular areas were arranged in a storiform pattern with a stroma formed by collagen and abundant vascularization. Tumor cells showed immunopositivity for CD34 and STAT-6 and no expression of CD99, AML, S-100, and Ki-67. According to these findings, the diagnosis of SFT was established. After 24 months, the patient is asymptomatic and has no evidence of recurrence. Although oral involvement is rare, SFT should be included in the differential diagnosis of oral submucosal lesions. 2022 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576069818063 https://www.redalyc.org/journal/5760/576069818063/ https://www.redalyc.org/journal/5760/576069818063/html/ https://www.redalyc.org/journal/5760/576069818063/576069818063.epub https://www.redalyc.org/journal/5760/576069818063/movil 10.4322/acr.2021.405 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.12 |
| title | Solitary fibrous tumor of the tongue |
| topic | Medicina Oral diagnosis Oral Pathology Solitary Fibrous Tumors |
| url | https://www.redalyc.org/articulo.oa?id=576069818063 https://www.redalyc.org/journal/5760/576069818063/ https://www.redalyc.org/journal/5760/576069818063/html/ https://www.redalyc.org/journal/5760/576069818063/576069818063.epub https://www.redalyc.org/journal/5760/576069818063/movil |