Saved in:
| Main Author: | |
|---|---|
| Format: | Artículo científico |
| Language: | en |
| Published: |
Hospital Universitário da Universidade de São Paulo
2023
|
| Subjects: | |
| Online Access: | https://www.redalyc.org/articulo.oa?id=576073999039 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Table of Contents:
- Clostridioides difficile infection leading to fulminant colitis with toxic megacolon Fareed Rajack Shawn Medford Tammey Naab Medicina Colitis Diarrhea Colectomy Pseudomembranous Colorectal Surgery Clostridioidesdifficile infection (CDI) is the culprit of millions of nosocomial infections in the United States. Programs that successfully decrease its incidence, therefore, render cost savings for the healthcare system. Toxic megacolon and perforation are two of the most significant complications with increased mortality rates. We report a 23-year-old nursing home resident hospitalized for fever, cough, and green sputum. After 3 days of antibiotic therapy, he developed abdominal distension, diarrhea, and vomiting and underwent a total colectomy. The colon was dilated to a maximum of 11 cm with markedly edematous mucosa and yellow pseudomembranes. Qualitative PCR of the stool detected Clostridioides difficile toxin B gene. While there is no consensus for the required interval between antibiotic treatment and CDI, this presentation 3 days after starting the antibiotic therapy is earlier than most proposed ranges. 2023 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576073999039 10.4322/acr.2023.457 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.13