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| Format: | Artículo científico |
| Language: | en |
| Published: |
Hospital Universitário da Universidade de São Paulo
2024
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| Subjects: | |
| Online Access: | https://www.redalyc.org/articulo.oa?id=576077572009 https://www.redalyc.org/journal/5760/576077572009/ https://www.redalyc.org/journal/5760/576077572009/html/ https://www.redalyc.org/journal/5760/576077572009/576077572009.epub https://www.redalyc.org/journal/5760/576077572009/movil |
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Table of Contents:
- Primary leiomyosarcoma with osteosarcomatous differentiation of the breast Ekta Sethi Sunayana Misra Arvind Ahuja Medicina Breast Sarcoma Mastectomy Leiomyosarcoma Primary leiomyosarcoma with osteosarcomatous differentiation of the breast is an uncommon entity. We present the case of a 37-year-old female who presented with a lump in the breast and pulmonary lesions on PET-CT, for which she underwent a toilet mastectomy. Histopathological examination revealed a tumor with cells arranged in sheets. These tumor cells had moderate eosinophilic cytoplasm, highly pleomorphic, irregular hyperchromatic nuclei, coarse chromatin, and prominent nucleoli. Areas with spindle-cell morphology were noted. Osteoid was seen intermingling with the tumor along with numerous osteoclast-like multinucleate giant cells. A wide panel of Immunohistochemistry was applied, and Desmin, h-Caldesmon, SMA, and Vimentin were positive. The patient died 3 months post-surgery and had a recurrence at the surgical site. 2024 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576077572009 https://www.redalyc.org/journal/5760/576077572009/ https://www.redalyc.org/journal/5760/576077572009/html/ https://www.redalyc.org/journal/5760/576077572009/576077572009.epub https://www.redalyc.org/journal/5760/576077572009/movil 10.4322/acr.2024.476 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.14