Exploring the unusual: a testosterone-secreting ovarian tumor
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| Format: | Artículo científico |
| Sprache: | en |
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Hospital Universitário da Universidade de São Paulo
2024
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| _version_ | 1876443905070727168 |
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| author | Harpreet Kaur |
| author_facet | Harpreet Kaur |
| contents | Exploring the unusual: a testosterone-secreting ovarian tumor Harpreet Kaur Neha Singh Sushma Bharti Gurwinder Kaur Medicina Sex Cord Hirsutism Postmenopause Ovarian neoplasm Gonadal Stromal Tumours Ovarian steroid cell tumors are rare, representing less than 0.1% of all ovarian neoplasms. Among the myriad causes of hirsutism, ovarian tumors account for 1% of the reported cases. We present the case of a 49-year-old parous postmenopausal woman who sought medical attention for hirsutism for 2 years. This case illustrates the unusual and interesting connection between rare ovarian pathology and the clinical manifestation of hirsutism in a postmenopausal patient. Her ultrasonography and MRI showed a right adnexal mass of solid-cystic consistency with thin septations. Her laboratory workup revealed high levels of total testosterone of 256 ng/ml (8.4-48.1ng/ml) and free testosterone of 7.36 pg/ml (0.2-4.1 pg/ml), while DHEAS - 234 µg/dl (35.4-256 µg/dl) and CA125 - 15.8U/L (0.0-35 U/L) were in the normal range. She underwent exploratory laparotomy with a total abdominal hysterectomy and oophorectomy. Histopathological examination and immunohistochemistry conclusively established the presence of a steroid cell tumor, specifically classified as "Not Otherwise Specified"(NOS), in the right ovary. 2024 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576077572011 https://www.redalyc.org/journal/5760/576077572011/ https://www.redalyc.org/journal/5760/576077572011/html/ https://www.redalyc.org/journal/5760/576077572011/576077572011.epub https://www.redalyc.org/journal/5760/576077572011/movil 10.4322/acr.2024.478 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.14 |
| format | Artículo científico |
| id | redalyc_576077572011 |
| institution | Redalyc |
| language | en |
| publishDate | 2024 |
| publisher | Hospital Universitário da Universidade de São Paulo |
| spellingShingle | Exploring the unusual: a testosterone-secreting ovarian tumor Harpreet Kaur Medicina Sex Cord Hirsutism Postmenopause Ovarian neoplasm Gonadal Stromal Tumours Exploring the unusual: a testosterone-secreting ovarian tumor Harpreet Kaur Neha Singh Sushma Bharti Gurwinder Kaur Medicina Sex Cord Hirsutism Postmenopause Ovarian neoplasm Gonadal Stromal Tumours Ovarian steroid cell tumors are rare, representing less than 0.1% of all ovarian neoplasms. Among the myriad causes of hirsutism, ovarian tumors account for 1% of the reported cases. We present the case of a 49-year-old parous postmenopausal woman who sought medical attention for hirsutism for 2 years. This case illustrates the unusual and interesting connection between rare ovarian pathology and the clinical manifestation of hirsutism in a postmenopausal patient. Her ultrasonography and MRI showed a right adnexal mass of solid-cystic consistency with thin septations. Her laboratory workup revealed high levels of total testosterone of 256 ng/ml (8.4-48.1ng/ml) and free testosterone of 7.36 pg/ml (0.2-4.1 pg/ml), while DHEAS - 234 µg/dl (35.4-256 µg/dl) and CA125 - 15.8U/L (0.0-35 U/L) were in the normal range. She underwent exploratory laparotomy with a total abdominal hysterectomy and oophorectomy. Histopathological examination and immunohistochemistry conclusively established the presence of a steroid cell tumor, specifically classified as "Not Otherwise Specified"(NOS), in the right ovary. 2024 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576077572011 https://www.redalyc.org/journal/5760/576077572011/ https://www.redalyc.org/journal/5760/576077572011/html/ https://www.redalyc.org/journal/5760/576077572011/576077572011.epub https://www.redalyc.org/journal/5760/576077572011/movil 10.4322/acr.2024.478 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.14 |
| title | Exploring the unusual: a testosterone-secreting ovarian tumor |
| topic | Medicina Sex Cord Hirsutism Postmenopause Ovarian neoplasm Gonadal Stromal Tumours |
| url | https://www.redalyc.org/articulo.oa?id=576077572011 https://www.redalyc.org/journal/5760/576077572011/ https://www.redalyc.org/journal/5760/576077572011/html/ https://www.redalyc.org/journal/5760/576077572011/576077572011.epub https://www.redalyc.org/journal/5760/576077572011/movil |