Papillary renal cell carcinoma with extensive spindle cell foci: mimicker of mucinous tubular and spindle cell carcinoma
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| Format: | Artículo científico |
| Language: | en |
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Hospital Universitário da Universidade de São Paulo
2024
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| _version_ | 1876428647345160192 |
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| author | Fareed Rajack |
| author_facet | Fareed Rajack |
| contents | Papillary renal cell carcinoma with extensive spindle cell foci: mimicker of mucinous tubular and spindle cell carcinoma Fareed Rajack Shawn Medford Tammey Naab Medicina Carcinoma Papillary Nephrectomy Kidney Neoplasms Immunohistochemistry Papillary renal cell carcinoma (PRCC) is the second most common renal cell carcinoma (RCC), accounting for 10-15% of cases. Mucinous tubular and spindle cell carcinoma (MTSCC), on the other hand, accounts for only 1% of renal tumors and has a more favorable prognosis compared to PRCC. We report a 75-year-old female with a left upper pole solid renal mass displaying features of both papillary renal cell carcinoma (PRCC) and mucinous tubular and spindle cell carcinoma (MTSC). In this case, a shaggy luminal surface, multiple papillations, and psammoma bodies, absence of E-cadherin expression, and strong CD10 expression favored PRCC. Both immunohistochemistry and genomic analysis are critical to diagnose and differentiate tumors that may have overlapping features accurately. 2024 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576077572012 https://www.redalyc.org/journal/5760/576077572012/ https://www.redalyc.org/journal/5760/576077572012/html/ https://www.redalyc.org/journal/5760/576077572012/576077572012.epub https://www.redalyc.org/journal/5760/576077572012/movil 10.4322/acr.2024.479 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.14 |
| format | Artículo científico |
| id | redalyc_576077572012 |
| institution | Redalyc |
| language | en |
| publishDate | 2024 |
| publisher | Hospital Universitário da Universidade de São Paulo |
| spellingShingle | Papillary renal cell carcinoma with extensive spindle cell foci: mimicker of mucinous tubular and spindle cell carcinoma Fareed Rajack Medicina Carcinoma Papillary Nephrectomy Kidney Neoplasms Immunohistochemistry Papillary renal cell carcinoma with extensive spindle cell foci: mimicker of mucinous tubular and spindle cell carcinoma Fareed Rajack Shawn Medford Tammey Naab Medicina Carcinoma Papillary Nephrectomy Kidney Neoplasms Immunohistochemistry Papillary renal cell carcinoma (PRCC) is the second most common renal cell carcinoma (RCC), accounting for 10-15% of cases. Mucinous tubular and spindle cell carcinoma (MTSCC), on the other hand, accounts for only 1% of renal tumors and has a more favorable prognosis compared to PRCC. We report a 75-year-old female with a left upper pole solid renal mass displaying features of both papillary renal cell carcinoma (PRCC) and mucinous tubular and spindle cell carcinoma (MTSC). In this case, a shaggy luminal surface, multiple papillations, and psammoma bodies, absence of E-cadherin expression, and strong CD10 expression favored PRCC. Both immunohistochemistry and genomic analysis are critical to diagnose and differentiate tumors that may have overlapping features accurately. 2024 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576077572012 https://www.redalyc.org/journal/5760/576077572012/ https://www.redalyc.org/journal/5760/576077572012/html/ https://www.redalyc.org/journal/5760/576077572012/576077572012.epub https://www.redalyc.org/journal/5760/576077572012/movil 10.4322/acr.2024.479 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.14 |
| title | Papillary renal cell carcinoma with extensive spindle cell foci: mimicker of mucinous tubular and spindle cell carcinoma |
| topic | Medicina Carcinoma Papillary Nephrectomy Kidney Neoplasms Immunohistochemistry |
| url | https://www.redalyc.org/articulo.oa?id=576077572012 https://www.redalyc.org/journal/5760/576077572012/ https://www.redalyc.org/journal/5760/576077572012/html/ https://www.redalyc.org/journal/5760/576077572012/576077572012.epub https://www.redalyc.org/journal/5760/576077572012/movil |