Neuroendocrine breast carcinoma
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| Format: | Artículo científico |
| Language: | en |
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Hospital Universitário da Universidade de São Paulo
2024
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| _version_ | 1876443350151725056 |
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| author | Laura Pratas Guerra |
| author_facet | Laura Pratas Guerra |
| contents | Neuroendocrine breast carcinoma Laura Pratas Guerra Joana Simões Diogo Carvalho Sá José Polónia António Araújo Medicina Carcinoma Pathology Breast Cancer Neuroendocrine Neuroendocrine breast cancer (NEBC) is a rare and heterogeneous entity. It most commonly presents a luminal phenotype and a worse prognosis. When diagnosed in an advanced stage, metastasis from another neuroendocrine tumor should be excluded.This case features a premenopausal woman with an oligometastatic breast large cell neuroendocrine carcinoma, estrogen receptor (ER) positive, and human epidermal growth factor receptor 2 (HER2) negative. Since the patient was very symptomatic at the presentation of the disease, chemotherapy was started. Complete radiological response of the metastatic disease was achieved, and the patient was then submitted to radical breast surgery and bilateral oophorectomy. She subsequently underwent radiation therapy. Since then and to date, she has been under endocrine therapy (ET) and a CDK4/6 inhibitor (CDK4/6i), with no evidence of malignant disease.Evidence to guide the choice of treatment for these tumors is currently scarce. In cases with oligometastatic disease, radical treatment should be considered. Given that this entity is rare, its reporting should be encouraged. 2024 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576077572015 https://www.redalyc.org/journal/5760/576077572015/ https://www.redalyc.org/journal/5760/576077572015/html/ https://www.redalyc.org/journal/5760/576077572015/576077572015.epub https://www.redalyc.org/journal/5760/576077572015/movil 10.4322/acr.2024.484 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.14 |
| format | Artículo científico |
| id | redalyc_576077572015 |
| institution | Redalyc |
| language | en |
| publishDate | 2024 |
| publisher | Hospital Universitário da Universidade de São Paulo |
| spellingShingle | Neuroendocrine breast carcinoma Laura Pratas Guerra Medicina Carcinoma Pathology Breast Cancer Neuroendocrine Neuroendocrine breast carcinoma Laura Pratas Guerra Joana Simões Diogo Carvalho Sá José Polónia António Araújo Medicina Carcinoma Pathology Breast Cancer Neuroendocrine Neuroendocrine breast cancer (NEBC) is a rare and heterogeneous entity. It most commonly presents a luminal phenotype and a worse prognosis. When diagnosed in an advanced stage, metastasis from another neuroendocrine tumor should be excluded.This case features a premenopausal woman with an oligometastatic breast large cell neuroendocrine carcinoma, estrogen receptor (ER) positive, and human epidermal growth factor receptor 2 (HER2) negative. Since the patient was very symptomatic at the presentation of the disease, chemotherapy was started. Complete radiological response of the metastatic disease was achieved, and the patient was then submitted to radical breast surgery and bilateral oophorectomy. She subsequently underwent radiation therapy. Since then and to date, she has been under endocrine therapy (ET) and a CDK4/6 inhibitor (CDK4/6i), with no evidence of malignant disease.Evidence to guide the choice of treatment for these tumors is currently scarce. In cases with oligometastatic disease, radical treatment should be considered. Given that this entity is rare, its reporting should be encouraged. 2024 otro 2236-1960 https://www.redalyc.org/articulo.oa?id=576077572015 https://www.redalyc.org/journal/5760/576077572015/ https://www.redalyc.org/journal/5760/576077572015/html/ https://www.redalyc.org/journal/5760/576077572015/576077572015.epub https://www.redalyc.org/journal/5760/576077572015/movil 10.4322/acr.2024.484 en http://www.redalyc.org/revista.oa?id=5760 Autopsy and Case Reports application/pdf Hospital Universitário da Universidade de São Paulo Autopsy and Case Reports (Brasil) Vol.14 |
| title | Neuroendocrine breast carcinoma |
| topic | Medicina Carcinoma Pathology Breast Cancer Neuroendocrine |
| url | https://www.redalyc.org/articulo.oa?id=576077572015 https://www.redalyc.org/journal/5760/576077572015/ https://www.redalyc.org/journal/5760/576077572015/html/ https://www.redalyc.org/journal/5760/576077572015/576077572015.epub https://www.redalyc.org/journal/5760/576077572015/movil |