El efecto del zolpidem en los pacientes con insomnio de corta evolución
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| Natura: | Artículo científico |
| Lingua: | en |
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Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
2001
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| _version_ | 1876482148867768320 |
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| author | J. Moisés Alvarez Rueda |
| author_facet | J. Moisés Alvarez Rueda |
| contents | El efecto del zolpidem en los pacientes con insomnio de corta evolución J. Moisés Alvarez Rueda Jesús Gutiérrez Aguilar Juan Rosales Alejandro Díaz Martínez Bruno C. Lablache Medicina Sleep treatment pharmacology sleep disorders benzodiazepines The wake-sleep cycle disorders are considered as health problems in ahigh percentage of the population. Insomnia is the more frequent sleepdisorder usually observed by the general practitioner, since it is accepted that its prevalence in the community is approximately 33%. Insomnia and the associated daytime fatigue also provoke discomforts that frequently are clinically meaningful because they are associated to drowsiness, anxiety,and lack of concentration and memory. These disorders induce socialand occupational deterioration or alterations in other important areasof the daily activity of the individuals. The initial therapeutic approximation to the patient with insomnia should be that of continually motivating him to acquire good sleep habits. Unfortunately, in some patientshaving good hygienic sleep habits is not sufficient, therefore hypnoticdrugs have to be prescribed during a short time in order to balance thedream/wake cycle. Benzodiazepines (BDZ) are among the available pharmacological agents usually prescribed. Unfortunately, when BDZ are administered, symptoms of tolerance or physical dependency may appear. Recently, other compounds were synthesized, such as zolpidem (ZPM),an sleep inductor with a novel structure and a particular neuropharmacological profile. This work was designed to show the clinical characteristics of ZPM, and compare them with those of a BDZ, the flunitrazepam (FNZ), in a group of patients with insomnia. This multicentric study includes100 ambulatory patients between 18 and 65 years, with a clinicaldiagnosis of primary insomnia. The evaluation of the treatment was accomplished through the application of Leeds Sleep Evaluation Questionnaire(QSEL), and the St. Mary´s Hospital Evaluation Questionnaire (SQSMH)... 2001 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58212406 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.1 Vol.24 |
| format | Artículo científico |
| id | redalyc_58212406 |
| institution | Redalyc |
| language | en |
| publishDate | 2001 |
| publisher | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz |
| spellingShingle | El efecto del zolpidem en los pacientes con insomnio de corta evolución J. Moisés Alvarez Rueda Medicina Sleep treatment pharmacology sleep disorders benzodiazepines El efecto del zolpidem en los pacientes con insomnio de corta evolución J. Moisés Alvarez Rueda Jesús Gutiérrez Aguilar Juan Rosales Alejandro Díaz Martínez Bruno C. Lablache Medicina Sleep treatment pharmacology sleep disorders benzodiazepines The wake-sleep cycle disorders are considered as health problems in ahigh percentage of the population. Insomnia is the more frequent sleepdisorder usually observed by the general practitioner, since it is accepted that its prevalence in the community is approximately 33%. Insomnia and the associated daytime fatigue also provoke discomforts that frequently are clinically meaningful because they are associated to drowsiness, anxiety,and lack of concentration and memory. These disorders induce socialand occupational deterioration or alterations in other important areasof the daily activity of the individuals. The initial therapeutic approximation to the patient with insomnia should be that of continually motivating him to acquire good sleep habits. Unfortunately, in some patientshaving good hygienic sleep habits is not sufficient, therefore hypnoticdrugs have to be prescribed during a short time in order to balance thedream/wake cycle. Benzodiazepines (BDZ) are among the available pharmacological agents usually prescribed. Unfortunately, when BDZ are administered, symptoms of tolerance or physical dependency may appear. Recently, other compounds were synthesized, such as zolpidem (ZPM),an sleep inductor with a novel structure and a particular neuropharmacological profile. This work was designed to show the clinical characteristics of ZPM, and compare them with those of a BDZ, the flunitrazepam (FNZ), in a group of patients with insomnia. This multicentric study includes100 ambulatory patients between 18 and 65 years, with a clinicaldiagnosis of primary insomnia. The evaluation of the treatment was accomplished through the application of Leeds Sleep Evaluation Questionnaire(QSEL), and the St. Mary´s Hospital Evaluation Questionnaire (SQSMH)... 2001 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58212406 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.1 Vol.24 |
| title | El efecto del zolpidem en los pacientes con insomnio de corta evolución |
| topic | Medicina Sleep treatment pharmacology sleep disorders benzodiazepines |
| url | https://www.redalyc.org/articulo.oa?id=58212406 |