Relapse and recurrence of depressed patients: a retrospective study
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| Natura: | Artículo científico |
| Lingua: | en |
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Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
2002
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| _version_ | 1876427954073894912 |
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| author | Valerio Villamil |
| author_facet | Valerio Villamil |
| contents | Relapse and recurrence of depressed patients: a retrospective study Valerio Villamil Gerardo Heinze José Cortés Medicina relapses Depression recurrences accumulated probability Ten per cent of the worlds overall population is affected bymajor depression. It is more common among 20-40 year oldwomen, young people living in cities, bachelors, and peoplehaving a family background of alcoholism and suicide.According to its presentation, depression is divided in singleand recidivant episodes, in remission, in recovery, in relapsingand in recurrence. While 50% of the depressed people recoverafter a one-year period, only 18% recover after four-years.Likewise, 70% of the subjects have subsequent depressiveepisodes, mainly related to stressing psycho-social events.The goal of this paper was to identify the accumulated probabilityof recurrence after the first and second major depressive episodes.During the first stage, 385 records belonging to majordepression subjects were reviewed. Through these records, thenumber of depressive symptoms each patient had through his/her lifetime; onset date; remission; whether patients receivedany specialized attention, and any periods of time where patientsshowed no symptoms were researched. Only those patientswho were first attended at this institute were included in thesecond stage. Two hundred and twenty-eight of them fell intothese criteria. For statistical analysis, X2 test, Kaplan-Meyerstest, and Log Rank test were used. Results showed the following average ages: 42 years for singleepisodes, 50 years for relapses, and 48 years for recurrences.While anxiety disorders were more commonly related to singleepisodes, cluster C appeared more frequently in the three groups;psycho-social stress was more closely related to relapses; theaccumulated probability of depression showed that the olderthe patient was, the higher the probability of having adepression relapse (r = 0.504; p = 0.0003). Tryciclics were themost commonly prescribed drugs in both stages. Whiledropping-out the treatment after a single major depressiveepisode significantly predicted recurrence (p= 0.002), it wasnot the case after a second depressive episode (p= 0.44).Although our results resemble those reported in theinternational bibliography, it would be advisable to expand oursample in the future. 2002 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58212502 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.1 Vol.25 |
| format | Artículo científico |
| id | redalyc_58212502 |
| institution | Redalyc |
| language | en |
| publishDate | 2002 |
| publisher | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz |
| spellingShingle | Relapse and recurrence of depressed patients: a retrospective study Valerio Villamil Medicina relapses Depression recurrences accumulated probability Relapse and recurrence of depressed patients: a retrospective study Valerio Villamil Gerardo Heinze José Cortés Medicina relapses Depression recurrences accumulated probability Ten per cent of the worlds overall population is affected bymajor depression. It is more common among 20-40 year oldwomen, young people living in cities, bachelors, and peoplehaving a family background of alcoholism and suicide.According to its presentation, depression is divided in singleand recidivant episodes, in remission, in recovery, in relapsingand in recurrence. While 50% of the depressed people recoverafter a one-year period, only 18% recover after four-years.Likewise, 70% of the subjects have subsequent depressiveepisodes, mainly related to stressing psycho-social events.The goal of this paper was to identify the accumulated probabilityof recurrence after the first and second major depressive episodes.During the first stage, 385 records belonging to majordepression subjects were reviewed. Through these records, thenumber of depressive symptoms each patient had through his/her lifetime; onset date; remission; whether patients receivedany specialized attention, and any periods of time where patientsshowed no symptoms were researched. Only those patientswho were first attended at this institute were included in thesecond stage. Two hundred and twenty-eight of them fell intothese criteria. For statistical analysis, X2 test, Kaplan-Meyerstest, and Log Rank test were used. Results showed the following average ages: 42 years for singleepisodes, 50 years for relapses, and 48 years for recurrences.While anxiety disorders were more commonly related to singleepisodes, cluster C appeared more frequently in the three groups;psycho-social stress was more closely related to relapses; theaccumulated probability of depression showed that the olderthe patient was, the higher the probability of having adepression relapse (r = 0.504; p = 0.0003). Tryciclics were themost commonly prescribed drugs in both stages. Whiledropping-out the treatment after a single major depressiveepisode significantly predicted recurrence (p= 0.002), it wasnot the case after a second depressive episode (p= 0.44).Although our results resemble those reported in theinternational bibliography, it would be advisable to expand oursample in the future. 2002 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58212502 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.1 Vol.25 |
| title | Relapse and recurrence of depressed patients: a retrospective study |
| topic | Medicina relapses Depression recurrences accumulated probability |
| url | https://www.redalyc.org/articulo.oa?id=58212502 |