Efectos residuales de la administración de hipnóticos sobre los patrones electroencefalográficos (PEEG) de voluntarios sanos
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| Format: | Artículo científico |
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Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
2000
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| author | Rodrigo Fernández |
| author_facet | Rodrigo Fernández |
| contents | Efectos residuales de la administración de hipnóticos sobre los patrones electroencefalográficos (PEEG) de voluntarios sanos Rodrigo Fernández Gustavo Luna Villegas Francisca Vera José Francisco Navarro Augusto Fernández Medicina GABOB diazepam zolpidem hypnotics zopiclone The aim of this study was to assess the possible residual effectsof a single nocturnal administration of benzodiazepine(diazepam 10 mg) and non-benzodiazepine hypnotics(zolpidem 10 mg; zopiclone 7.5 mg; GABOB 500 mg) oncortical activation 9 and 33 h after oral intake in healthyvolunteers, using an extended Youden square design. Theelectro-encephalographic segments (EEG) delimited by asequence of photic stimuli presented every 10 sec during asimple reaction-time task (37 min duration) were classified intonine cerebral patterns (EEGP). EEGP segment classificationswere grouped into six transitions: (1) alpha-blockade, (2) alphapersistence,(3) beta-persistence, (4) alpha-induction, (5)activation, and (6) deactivation. The results indicated thatGABOB provoked significant changes in EEGP transitions, similarto those usually showed by benzodiazepines. Zolpidemproduced a significant amount of alpha blockades 33 h afterits administration. By contrast, diazepam and zopiclone didnot modify significantly cortical EEG activity. 2000 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58222305 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.2 Vol.23 |
| format | Artículo científico |
| id | redalyc_58222305 |
| institution | Redalyc |
| language | en |
| publishDate | 2000 |
| publisher | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz |
| spellingShingle | Efectos residuales de la administración de hipnóticos sobre los patrones electroencefalográficos (PEEG) de voluntarios sanos Rodrigo Fernández Medicina GABOB diazepam zolpidem hypnotics zopiclone Efectos residuales de la administración de hipnóticos sobre los patrones electroencefalográficos (PEEG) de voluntarios sanos Rodrigo Fernández Gustavo Luna Villegas Francisca Vera José Francisco Navarro Augusto Fernández Medicina GABOB diazepam zolpidem hypnotics zopiclone The aim of this study was to assess the possible residual effectsof a single nocturnal administration of benzodiazepine(diazepam 10 mg) and non-benzodiazepine hypnotics(zolpidem 10 mg; zopiclone 7.5 mg; GABOB 500 mg) oncortical activation 9 and 33 h after oral intake in healthyvolunteers, using an extended Youden square design. Theelectro-encephalographic segments (EEG) delimited by asequence of photic stimuli presented every 10 sec during asimple reaction-time task (37 min duration) were classified intonine cerebral patterns (EEGP). EEGP segment classificationswere grouped into six transitions: (1) alpha-blockade, (2) alphapersistence,(3) beta-persistence, (4) alpha-induction, (5)activation, and (6) deactivation. The results indicated thatGABOB provoked significant changes in EEGP transitions, similarto those usually showed by benzodiazepines. Zolpidemproduced a significant amount of alpha blockades 33 h afterits administration. By contrast, diazepam and zopiclone didnot modify significantly cortical EEG activity. 2000 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58222305 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.2 Vol.23 |
| title | Efectos residuales de la administración de hipnóticos sobre los patrones electroencefalográficos (PEEG) de voluntarios sanos |
| topic | Medicina GABOB diazepam zolpidem hypnotics zopiclone |
| url | https://www.redalyc.org/articulo.oa?id=58222305 |