Nicotine antidepressant effects as a predictor of response to desimipramine or fluoxetine in non-smoking major depressed patients
Fuente:
Redalyc
Saved in:
| Main Author: | |
|---|---|
| Format: | Artículo científico |
| Language: | en |
| Published: |
Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
2002
|
| Subjects: | |
| Online Access: | |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1876482297323061248 |
|---|---|
| author | Rafael J. Salín Pascual |
| author_facet | Rafael J. Salín Pascual |
| contents | Nicotine antidepressant effects as a predictor of response to desimipramine or fluoxetine in non-smoking major depressed patients Rafael J. Salín Pascual Medicina nicotine fluoxetine desimipramine Major depression It has been reported that there is a link between majordepression and nicotine dependence. Also, it has beenshown that acute administration from one to fourcontinuous days of transdermal nicotine improveddepression in non-smoking major depressed patients.The goals of this study were to observe the antidepressanteffect of transdermal nicotine in placebonon-responders non-smoking major depressed patients,after one week of daily nicotine administration, and tosee if the antidepressant response to nicotine couldpredict the clinical outcome after fluoxetine ordesimipramine administration.Forty-two non-smoking major depressed patients werestudied. After a complete explanation about theprotocol, signed consents were obtained from all thesubjects. Patients received placebo during two weeks.Placebo responders were removed from the study.Placebo non-responders patients received one-weektransdermal nicotine patches (17.5 mg/24 hr) andplacebo capsules for one week. Subsequently thepatients were randomly assigned to desimipramine (150mg/day) or fluoxetine (20 mg/day). Weekly visits wereevaluated using both clinical scales, during six followupvisits... 2002 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58222503 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.2 Vol.25 |
| format | Artículo científico |
| id | redalyc_58222503 |
| institution | Redalyc |
| language | en |
| publishDate | 2002 |
| publisher | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz |
| spellingShingle | Nicotine antidepressant effects as a predictor of response to desimipramine or fluoxetine in non-smoking major depressed patients Rafael J. Salín Pascual Medicina nicotine fluoxetine desimipramine Major depression Nicotine antidepressant effects as a predictor of response to desimipramine or fluoxetine in non-smoking major depressed patients Rafael J. Salín Pascual Medicina nicotine fluoxetine desimipramine Major depression It has been reported that there is a link between majordepression and nicotine dependence. Also, it has beenshown that acute administration from one to fourcontinuous days of transdermal nicotine improveddepression in non-smoking major depressed patients.The goals of this study were to observe the antidepressanteffect of transdermal nicotine in placebonon-responders non-smoking major depressed patients,after one week of daily nicotine administration, and tosee if the antidepressant response to nicotine couldpredict the clinical outcome after fluoxetine ordesimipramine administration.Forty-two non-smoking major depressed patients werestudied. After a complete explanation about theprotocol, signed consents were obtained from all thesubjects. Patients received placebo during two weeks.Placebo responders were removed from the study.Placebo non-responders patients received one-weektransdermal nicotine patches (17.5 mg/24 hr) andplacebo capsules for one week. Subsequently thepatients were randomly assigned to desimipramine (150mg/day) or fluoxetine (20 mg/day). Weekly visits wereevaluated using both clinical scales, during six followupvisits... 2002 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58222503 en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.2 Vol.25 |
| title | Nicotine antidepressant effects as a predictor of response to desimipramine or fluoxetine in non-smoking major depressed patients |
| topic | Medicina nicotine fluoxetine desimipramine Major depression |
| url | https://www.redalyc.org/articulo.oa?id=58222503 |