An integrative overview of the cannabinergic system and mental health
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| Natura: | Artículo científico |
| Lingua: | en |
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Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
2017
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| _version_ | 1876455406253899776 |
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| author | Oscar E. Prospéro García |
| author_facet | Oscar E. Prospéro García |
| contents | An integrative overview of the cannabinergic system and mental health Oscar E. Prospéro García Pavel E. Rueda Orozco Octavio Amancio Belmont Alejandra E. Ruiz Contreras Mónica Méndez Díaz Medicina mental health endocannabinoids Cannabinoid system cannabinoid receptor 1 cannabinoid receptor 2 Background. The endocannabinoid system (eCBs) is one of the modulatory systems widely expressed in the brain. It consists of receptors expressed in the cytoplasmic (CB1 and CB2), the mitochondrial membrane (CB1), and the endogenous ligands known as endocannabinoids, such as anandamide, 2AG and oleam - ide. CB1 has been found in excitatory and inhibitory neurons in the pre- and post-synaptic membranes. It is expressed in several brain areas such as the hippocampus, dorsal, and ventral striatum, amygdala and prefrontal cortex. The eCBs has been involved in the regulation of learning and memory, mood, energy bal- ance, sleep, and drug addiction. Objective. Integrate existing information about the eCBs and its role in brain function and mental health. Method. Review of the information of basic and clinical relevance obtained from indexed scientific journals (PubMed/Medline, Scopus). Results. Basic and clinical research on eCBs related to central nervous system function is described. Discussion and conclusion. At present, the study of eCBs is of importance. The development of drugs that affect this system may be clinically useful to control different debilitating diseases. This is an area of interest to the scientific community and health care providers. 2017 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58251633005 https://www.redalyc.org/journal/582/58251633005/ https://www.redalyc.org/journal/582/58251633005/html/ https://www.redalyc.org/journal/582/58251633005/58251633005.epub https://www.redalyc.org/journal/582/58251633005/movil en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.3 Vol.40 |
| format | Artículo científico |
| id | redalyc_58251633005 |
| institution | Redalyc |
| language | en |
| publishDate | 2017 |
| publisher | Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz |
| spellingShingle | An integrative overview of the cannabinergic system and mental health Oscar E. Prospéro García Medicina mental health endocannabinoids Cannabinoid system cannabinoid receptor 1 cannabinoid receptor 2 An integrative overview of the cannabinergic system and mental health Oscar E. Prospéro García Pavel E. Rueda Orozco Octavio Amancio Belmont Alejandra E. Ruiz Contreras Mónica Méndez Díaz Medicina mental health endocannabinoids Cannabinoid system cannabinoid receptor 1 cannabinoid receptor 2 Background. The endocannabinoid system (eCBs) is one of the modulatory systems widely expressed in the brain. It consists of receptors expressed in the cytoplasmic (CB1 and CB2), the mitochondrial membrane (CB1), and the endogenous ligands known as endocannabinoids, such as anandamide, 2AG and oleam - ide. CB1 has been found in excitatory and inhibitory neurons in the pre- and post-synaptic membranes. It is expressed in several brain areas such as the hippocampus, dorsal, and ventral striatum, amygdala and prefrontal cortex. The eCBs has been involved in the regulation of learning and memory, mood, energy bal- ance, sleep, and drug addiction. Objective. Integrate existing information about the eCBs and its role in brain function and mental health. Method. Review of the information of basic and clinical relevance obtained from indexed scientific journals (PubMed/Medline, Scopus). Results. Basic and clinical research on eCBs related to central nervous system function is described. Discussion and conclusion. At present, the study of eCBs is of importance. The development of drugs that affect this system may be clinically useful to control different debilitating diseases. This is an area of interest to the scientific community and health care providers. 2017 artículo científico 0185-3325 https://www.redalyc.org/articulo.oa?id=58251633005 https://www.redalyc.org/journal/582/58251633005/ https://www.redalyc.org/journal/582/58251633005/html/ https://www.redalyc.org/journal/582/58251633005/58251633005.epub https://www.redalyc.org/journal/582/58251633005/movil en http://www.redalyc.org/revista.oa?id=582 Salud Mental application/pdf Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz Salud Mental (México) Num.3 Vol.40 |
| title | An integrative overview of the cannabinergic system and mental health |
| topic | Medicina mental health endocannabinoids Cannabinoid system cannabinoid receptor 1 cannabinoid receptor 2 |
| url | https://www.redalyc.org/articulo.oa?id=58251633005 https://www.redalyc.org/journal/582/58251633005/ https://www.redalyc.org/journal/582/58251633005/html/ https://www.redalyc.org/journal/582/58251633005/58251633005.epub https://www.redalyc.org/journal/582/58251633005/movil |