Effect of Dentoxol® in the treatment of recurrent mild aphthous ulcers. A prospective observational pilot study
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| Format: | Artículo científico |
| Langue: | en |
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Sociedad de Periodoncia de Chile
2022
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| _version_ | 1876487963750170624 |
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| author | D. Rosenberg |
| author_facet | D. Rosenberg |
| contents | Effect of Dentoxol® in the treatment of recurrent mild aphthous ulcers. A prospective observational pilot study D. Rosenberg B. Martínez N. Carrasco T. Galván Medicina Dentoxol Mouthrinse Recurrent aphthous stomatitis Background: Recurrent aphthous stomatitis (RAS) is the most common oral ulceration. Its prevalence in the general population varies between 5% and 60%, and during the acute period, it causes pain and interferes with basic activities, such as eating, swallowing and talking. Dentoxol® is a medical mouthrinse that cleans, moisturizes and lubricates the mouth, mechanically stimulating local epithelial regeneration. The aim of this study was to evaluate the efficacy of Dentoxol® in improving the general state of patient with minor RAS using two different treatment schemes. Material and methods: Thirty-nine patients with RAS were recruited in a prospective observational pilot study. Two dosing regimens, 5 ml of Dentoxol® twice daily and 5 ml of Dentoxol® three times daily were evaluated. Results: Efficacy to improve the general state was significant superior in “Three time daily” group compared with “twice daily” at 72 h (66% vs 33% respectively). No pain was reported in approximately 90% of cases at 96 h of use in both group without significant differences between the groups in any evaluation time-point. Conclusion: Despite the limitations of these preliminary data, Dentoxol® shows promising beneficial properties for the management of minor RAS. 2022 artículo científico 2452-5588 https://www.redalyc.org/articulo.oa?id=610071148006 https://www.redalyc.org/journal/6100/610071148006/ https://www.redalyc.org/journal/6100/610071148006/html/ https://www.redalyc.org/journal/6100/610071148006/610071148006.epub https://www.redalyc.org/journal/6100/610071148006/movil 10.4067/S2452-55882022000100025 en http://www.redalyc.org/revista.oa?id=6100 International Journal of Interdisciplinary Dentistry application/pdf Sociedad de Periodoncia de Chile International Journal of Interdisciplinary Dentistry (Chile) Num.1 Vol.15 |
| format | Artículo científico |
| id | redalyc_610071148006 |
| institution | Redalyc |
| language | en |
| publishDate | 2022 |
| publisher | Sociedad de Periodoncia de Chile |
| spellingShingle | Effect of Dentoxol® in the treatment of recurrent mild aphthous ulcers. A prospective observational pilot study D. Rosenberg Medicina Dentoxol Mouthrinse Recurrent aphthous stomatitis Effect of Dentoxol® in the treatment of recurrent mild aphthous ulcers. A prospective observational pilot study D. Rosenberg B. Martínez N. Carrasco T. Galván Medicina Dentoxol Mouthrinse Recurrent aphthous stomatitis Background: Recurrent aphthous stomatitis (RAS) is the most common oral ulceration. Its prevalence in the general population varies between 5% and 60%, and during the acute period, it causes pain and interferes with basic activities, such as eating, swallowing and talking. Dentoxol® is a medical mouthrinse that cleans, moisturizes and lubricates the mouth, mechanically stimulating local epithelial regeneration. The aim of this study was to evaluate the efficacy of Dentoxol® in improving the general state of patient with minor RAS using two different treatment schemes. Material and methods: Thirty-nine patients with RAS were recruited in a prospective observational pilot study. Two dosing regimens, 5 ml of Dentoxol® twice daily and 5 ml of Dentoxol® three times daily were evaluated. Results: Efficacy to improve the general state was significant superior in “Three time daily” group compared with “twice daily” at 72 h (66% vs 33% respectively). No pain was reported in approximately 90% of cases at 96 h of use in both group without significant differences between the groups in any evaluation time-point. Conclusion: Despite the limitations of these preliminary data, Dentoxol® shows promising beneficial properties for the management of minor RAS. 2022 artículo científico 2452-5588 https://www.redalyc.org/articulo.oa?id=610071148006 https://www.redalyc.org/journal/6100/610071148006/ https://www.redalyc.org/journal/6100/610071148006/html/ https://www.redalyc.org/journal/6100/610071148006/610071148006.epub https://www.redalyc.org/journal/6100/610071148006/movil 10.4067/S2452-55882022000100025 en http://www.redalyc.org/revista.oa?id=6100 International Journal of Interdisciplinary Dentistry application/pdf Sociedad de Periodoncia de Chile International Journal of Interdisciplinary Dentistry (Chile) Num.1 Vol.15 |
| title | Effect of Dentoxol® in the treatment of recurrent mild aphthous ulcers. A prospective observational pilot study |
| topic | Medicina Dentoxol Mouthrinse Recurrent aphthous stomatitis |
| url | https://www.redalyc.org/articulo.oa?id=610071148006 https://www.redalyc.org/journal/6100/610071148006/ https://www.redalyc.org/journal/6100/610071148006/html/ https://www.redalyc.org/journal/6100/610071148006/610071148006.epub https://www.redalyc.org/journal/6100/610071148006/movil |