Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil
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| Formato: | Artículo científico |
| Lenguaje: | en |
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Universidade de São Paulo
2008
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| _version_ | 1876484476159131648 |
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| author | E M M Huatuco |
| author_facet | E M M Huatuco |
| contents | Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil E M M Huatuco E L Durigon F L A S Lebrun S D Passos R E Gazeta R S Azevedo Neto E Massad Salud Human Risk Groups epidemiology Parvovirus B19 Parvoviridae Infections OBJECTIVE: To analyze the prevalence of IgG antibodies to human parvovirus B19. METHODS: Cross-sectional study in a suburban community in São Paulo, Southeastern Brazil, between November 1990 and January 1991. Randomly selected (N=435) representative samples of sera were collected from healthy children older than 15 days old and adults up to 40 years old. IgG antibodies were detected using ELISA. RESULTS: High prevalence of IgG antibodies to B19 parvovirus was found in 87% of newborns. The prevalence of maternally derived IgG antibodies exponentially plunged up to the 19th month of age. Low prevalence of antibodies was found in the fi rst 4 years of life, increasing up to 72% in those aged 31-40 years. It was estimated that the average age of fi rst infection in this population is 21 ± 7 years old and the optimal age for vaccination with a hypothetical vaccine would be 1 year of age. CONCLUSIONS: Parvovirus B19 IgG antibody prevalence was high in newborns and those aged 31-40 years. The analysis by age groups showed a pattern similar to that found in previous studies, i.e., low prevalence of infection in children that increases with age. 2008 artículo científico 0034-8910 https://www.redalyc.org/articulo.oa?id=67240168008 en http://www.redalyc.org/revista.oa?id=672 Revista de Saúde Pública application/pdf Universidade de São Paulo Revista de Saúde Pública (Brasil) Num.3 Vol.42 |
| format | Artículo científico |
| id | redalyc_67240168008 |
| institution | Redalyc |
| language | en |
| publishDate | 2008 |
| publisher | Universidade de São Paulo |
| spellingShingle | Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil E M M Huatuco Salud Human Risk Groups epidemiology Parvovirus B19 Parvoviridae Infections Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil E M M Huatuco E L Durigon F L A S Lebrun S D Passos R E Gazeta R S Azevedo Neto E Massad Salud Human Risk Groups epidemiology Parvovirus B19 Parvoviridae Infections OBJECTIVE: To analyze the prevalence of IgG antibodies to human parvovirus B19. METHODS: Cross-sectional study in a suburban community in São Paulo, Southeastern Brazil, between November 1990 and January 1991. Randomly selected (N=435) representative samples of sera were collected from healthy children older than 15 days old and adults up to 40 years old. IgG antibodies were detected using ELISA. RESULTS: High prevalence of IgG antibodies to B19 parvovirus was found in 87% of newborns. The prevalence of maternally derived IgG antibodies exponentially plunged up to the 19th month of age. Low prevalence of antibodies was found in the fi rst 4 years of life, increasing up to 72% in those aged 31-40 years. It was estimated that the average age of fi rst infection in this population is 21 ± 7 years old and the optimal age for vaccination with a hypothetical vaccine would be 1 year of age. CONCLUSIONS: Parvovirus B19 IgG antibody prevalence was high in newborns and those aged 31-40 years. The analysis by age groups showed a pattern similar to that found in previous studies, i.e., low prevalence of infection in children that increases with age. 2008 artículo científico 0034-8910 https://www.redalyc.org/articulo.oa?id=67240168008 en http://www.redalyc.org/revista.oa?id=672 Revista de Saúde Pública application/pdf Universidade de São Paulo Revista de Saúde Pública (Brasil) Num.3 Vol.42 |
| title | Seroprevalence of human parvovirus B19 in a suburban population in São Paulo, Brazil |
| topic | Salud Human Risk Groups epidemiology Parvovirus B19 Parvoviridae Infections |
| url | https://www.redalyc.org/articulo.oa?id=67240168008 |