Body mass index for predicting hyperglycemia and serum lipid changes in Brazilian adolescents

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Auteur principal: Ana Carolina R Vieira
Format: Artículo científico
Langue:en
Publié: Universidade de São Paulo 2009
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author Ana Carolina R Vieira
author_facet Ana Carolina R Vieira
contents Body mass index for predicting hyperglycemia and serum lipid changes in Brazilian adolescents Ana Carolina R Vieira Marlene M Alvarez Salim Kanaan Rosely Sichieri Gloria V Veiga Salud Adolescent Risk Factors Hyperglycemia Body Mass Index Hyperlipidemias OBJECTIVE: To determine the best cut-offs of body mass index for identifying alterations of blood lipids and glucose in adolescents. METHODS: A probabilistic sample including 577 adolescent students aged 12-19 years in 2003 (210 males and 367 females) from state public schools in the city of Niterói, Southeastern Brazil, was studied. The Receiver Operating Characteristic curve was used to identify the best age-adjusted BMI cut-off for predicting high levels of serum total cholesterol (≥150mg/dL), LDL-C (≥ 100mg/dL), serum triglycerides (≥100mg/dL), plasma glucose (>100mg/dL) and low levels of HDL-C (< 45mg/dL). Four references were used to calculate sensitivity and specifi city of BMI cut-offs: one Brazilian, one international and two American. RESULTS: The most prevalent metabolic alterations (>50%) were: high total cholesterol and low HDL-C. BMI predicted high levels of triglycerides in males, high LDL-C in females, and high total cholesterol and the occurrence of three or more metabolic alterations in both males and females (areas under the curve range: 0.59 to 0.67), with low sensitivity (57%–66%) and low specifi city (58%–66%). The best BMI cut-offs for this sample (20.3 kg/m² to 21.0 kg/m²) were lower than those proposed in the references studied. CONCLUSIONS: Although BMI values lower than the International cutoffs were better predictor of some metabolic abnormalities in Brazilian adolescents, overall BMI is not a good predictor of these abnormalities in this population. 2009 artículo científico 0034-8910 https://www.redalyc.org/articulo.oa?id=67240174006 en http://www.redalyc.org/revista.oa?id=672 Revista de Saúde Pública application/pdf Universidade de São Paulo Revista de Saúde Pública (Brasil) Num.1 Vol.43
format Artículo científico
id redalyc_67240174006
institution Redalyc
language en
publishDate 2009
publisher Universidade de São Paulo
spellingShingle Body mass index for predicting hyperglycemia and serum lipid changes in Brazilian adolescents
Ana Carolina R Vieira
Salud
Adolescent
Risk Factors
Hyperglycemia
Body Mass Index
Hyperlipidemias
Body mass index for predicting hyperglycemia and serum lipid changes in Brazilian adolescents Ana Carolina R Vieira Marlene M Alvarez Salim Kanaan Rosely Sichieri Gloria V Veiga Salud Adolescent Risk Factors Hyperglycemia Body Mass Index Hyperlipidemias OBJECTIVE: To determine the best cut-offs of body mass index for identifying alterations of blood lipids and glucose in adolescents. METHODS: A probabilistic sample including 577 adolescent students aged 12-19 years in 2003 (210 males and 367 females) from state public schools in the city of Niterói, Southeastern Brazil, was studied. The Receiver Operating Characteristic curve was used to identify the best age-adjusted BMI cut-off for predicting high levels of serum total cholesterol (≥150mg/dL), LDL-C (≥ 100mg/dL), serum triglycerides (≥100mg/dL), plasma glucose (>100mg/dL) and low levels of HDL-C (< 45mg/dL). Four references were used to calculate sensitivity and specifi city of BMI cut-offs: one Brazilian, one international and two American. RESULTS: The most prevalent metabolic alterations (>50%) were: high total cholesterol and low HDL-C. BMI predicted high levels of triglycerides in males, high LDL-C in females, and high total cholesterol and the occurrence of three or more metabolic alterations in both males and females (areas under the curve range: 0.59 to 0.67), with low sensitivity (57%–66%) and low specifi city (58%–66%). The best BMI cut-offs for this sample (20.3 kg/m² to 21.0 kg/m²) were lower than those proposed in the references studied. CONCLUSIONS: Although BMI values lower than the International cutoffs were better predictor of some metabolic abnormalities in Brazilian adolescents, overall BMI is not a good predictor of these abnormalities in this population. 2009 artículo científico 0034-8910 https://www.redalyc.org/articulo.oa?id=67240174006 en http://www.redalyc.org/revista.oa?id=672 Revista de Saúde Pública application/pdf Universidade de São Paulo Revista de Saúde Pública (Brasil) Num.1 Vol.43
title Body mass index for predicting hyperglycemia and serum lipid changes in Brazilian adolescents
topic Salud
Adolescent
Risk Factors
Hyperglycemia
Body Mass Index
Hyperlipidemias
url https://www.redalyc.org/articulo.oa?id=67240174006