HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil
Fuente:
Redalyc
Salvato in:
| Autore principale: | |
|---|---|
| Natura: | Artículo científico |
| Lingua: | en |
| Pubblicazione: |
Universidade de São Paulo
2010
|
| Soggetti: | |
| Accesso online: | |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
|
| _version_ | 1876465805253672960 |
|---|---|
| author | Valdiléa G Veloso |
| author_facet | Valdiléa G Veloso |
| contents | HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil Valdiléa G Veloso Francisco I Bastos Margareth Crisóstomo Portela Beatriz Grinsztejn Esau Custodio João Jose Henrique da Silva Pilotto Ana Beatriz Busch Araújo Breno Riegel Santos Rosana Campos da Fonseca Regis Kreitchmann Monica Derrico Ruth Khalili Friedman Cynthia B Cunha Mariza Gonçalves Morgado Karin Nielsen Saines Yvonne J Bryson Salud Vertical diagnosis Prenatal Care Pregnant Women Breast Feeding OBJECTIVE: To assess the feasibility of HIV rapid testing for pregnant womenat maternity hospital admission and of subsequent interventions to reduceperinatal HIV transmission.METHODS: Study based on a convenience sample of women unaware oftheir HIV serostatus when they were admitted to delivery in public maternityhospitals in Rio de Janeiro and Porto Alegre, Brazil, between March 2000 andApril 2002. Women were counseled and tested using the Determine HIV1/2Rapid Test. HIV infection was confi rmed using the Brazilian algorithm for HIVinfection diagnosis. In utero transmission of HIV was determined using HIVDNA-PCR. There were performed descriptive analyses of sociodemographicdata, number of previous pregnancies and abortions, number of prenatal carevisits, timing of HIV testing, HIV rapid test result, neonatal and mother-tochildtransmission interventions, by city studied.RESULTS: HIV prevalence in women was 6.5% (N=1,439) in Porto Alegreand 1.3% (N=3.778) in Rio de Janeiro. In Porto Alegre most of women weretested during labor (88.7%), while in Rio de Janeiro most were tested in thepostpartum (67.5%). One hundred and forty-four infants were born to 143 HIVinfectedwomen. All newborns but one in each city received at least prophylaxiswith oral zidovudine. It was possible to completely avoid newborn exposureto breast milk in 96.8% and 51.1% of the cases in Porto Alegre and Rio deJaneiro, respectively. Injectable intravenous zidovudine was administeredduring labor to 68.8% and 27.7% newborns in Porto Alegre and Rio de Janeiro,respectively. Among those from whom blood samples were collected within48 hours of birth, in utero transmission of HIV was confi rmed in 4 cases inRio de Janeiro (4/47) and 6 cases in Porto Alegre (6/79).CONCLUSIONS: The strategy proved feasible in maternity hospitals in Riode Janeiro and Porto Alegre. Efforts must be taken to maximize HIV testingduring labor. There is a need of strong social support to provide this populationaccess to health care services after hospital discharge. 2010 artículo científico 0034-8910 https://www.redalyc.org/articulo.oa?id=67240187005 en http://www.redalyc.org/revista.oa?id=672 Revista de Saúde Pública application/pdf Universidade de São Paulo Revista de Saúde Pública (Brasil) Num.5 Vol.44 |
| format | Artículo científico |
| id | redalyc_67240187005 |
| institution | Redalyc |
| language | en |
| publishDate | 2010 |
| publisher | Universidade de São Paulo |
| spellingShingle | HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil Valdiléa G Veloso Salud Vertical diagnosis Prenatal Care Pregnant Women Breast Feeding HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil Valdiléa G Veloso Francisco I Bastos Margareth Crisóstomo Portela Beatriz Grinsztejn Esau Custodio João Jose Henrique da Silva Pilotto Ana Beatriz Busch Araújo Breno Riegel Santos Rosana Campos da Fonseca Regis Kreitchmann Monica Derrico Ruth Khalili Friedman Cynthia B Cunha Mariza Gonçalves Morgado Karin Nielsen Saines Yvonne J Bryson Salud Vertical diagnosis Prenatal Care Pregnant Women Breast Feeding OBJECTIVE: To assess the feasibility of HIV rapid testing for pregnant womenat maternity hospital admission and of subsequent interventions to reduceperinatal HIV transmission.METHODS: Study based on a convenience sample of women unaware oftheir HIV serostatus when they were admitted to delivery in public maternityhospitals in Rio de Janeiro and Porto Alegre, Brazil, between March 2000 andApril 2002. Women were counseled and tested using the Determine HIV1/2Rapid Test. HIV infection was confi rmed using the Brazilian algorithm for HIVinfection diagnosis. In utero transmission of HIV was determined using HIVDNA-PCR. There were performed descriptive analyses of sociodemographicdata, number of previous pregnancies and abortions, number of prenatal carevisits, timing of HIV testing, HIV rapid test result, neonatal and mother-tochildtransmission interventions, by city studied.RESULTS: HIV prevalence in women was 6.5% (N=1,439) in Porto Alegreand 1.3% (N=3.778) in Rio de Janeiro. In Porto Alegre most of women weretested during labor (88.7%), while in Rio de Janeiro most were tested in thepostpartum (67.5%). One hundred and forty-four infants were born to 143 HIVinfectedwomen. All newborns but one in each city received at least prophylaxiswith oral zidovudine. It was possible to completely avoid newborn exposureto breast milk in 96.8% and 51.1% of the cases in Porto Alegre and Rio deJaneiro, respectively. Injectable intravenous zidovudine was administeredduring labor to 68.8% and 27.7% newborns in Porto Alegre and Rio de Janeiro,respectively. Among those from whom blood samples were collected within48 hours of birth, in utero transmission of HIV was confi rmed in 4 cases inRio de Janeiro (4/47) and 6 cases in Porto Alegre (6/79).CONCLUSIONS: The strategy proved feasible in maternity hospitals in Riode Janeiro and Porto Alegre. Efforts must be taken to maximize HIV testingduring labor. There is a need of strong social support to provide this populationaccess to health care services after hospital discharge. 2010 artículo científico 0034-8910 https://www.redalyc.org/articulo.oa?id=67240187005 en http://www.redalyc.org/revista.oa?id=672 Revista de Saúde Pública application/pdf Universidade de São Paulo Revista de Saúde Pública (Brasil) Num.5 Vol.44 |
| title | HIV rapid testing as a key strategy for prevention of mother-to-child transmission in Brazil |
| topic | Salud Vertical diagnosis Prenatal Care Pregnant Women Breast Feeding |
| url | https://www.redalyc.org/articulo.oa?id=67240187005 |