Pattern and quality of scientific communications on drug safety produced by a regional pharmacovigilance center in Nepal
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| Format: | Artículo científico |
| Language: | en |
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Centro de investigaciones y Publicaciones Farmacéuticas
2010
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| author | Subish PALAIAN |
| author_facet | Subish PALAIAN |
| contents | Pattern and quality of scientific communications on drug safety produced by a regional pharmacovigilance center in Nepal Subish PALAIAN Mohamed I. M. IBRAHIM Pranaya MISHRA Medicina Nepal Periodicals as Topic Adverse Drug Reaction Reporting Systems Analyzing the pattern and quality of scientific communications on pharmacovigilance can help the regional centers in Nepal and other developing countries to develop approaches for communicating effectively medicine safety issues. This kind of research is lacking in developing countries. Objectives: To analyze the pattern and quality of scientific communications on drug safety produced by the regional pharmacovigilance center at western Nepal. Methodology: Various conference abstracts and journal publications produced by the center during its initial four years of establishment (14th September 2004 till 13th September 2008) were identified. These communications were categorized in to case reports, review articles, conference presentations, short communications, newsletter and bulletin articles, original research and case series. In addition, the quality of the case reports were evaluated as per International Society of Pharmacovigilance/International Society of Pharmacoepidemiology (ISoP/ISPE) guidelines on the requirements for submitting case reports on adverse event reports in biomedical journals.Results: During the study period, 53 scientific communications were produced by the staff of the regional pharmacovigilance center in relation with drug safety. Among these, 18 (34%) were related to case reports and letters. The median (interquartile range) age of the patients described in the case reports was 46.5 (21.7-51.2) years. Among the total 18 ADRs, four were fixed drug eruptions, followed by contact dermatitis (n=2). Majority of the published case reports were related to skin (n=13; 72.2%). Antimicrobials were responsible for 27.8% (n=5) of the case reports. Among the 18 case reports published by the pharmacovigilance center, a majority followed the ISoP/ISPE guidelines. Few parameters like physical examination of the patient experiencing ADR, patient disposition, dosage and administration of the suspected drugs, and drugreaction interface were missing in few of the cases. Conclusion: A high percentage of the scientific communications were "case reports". A high proportion of the case reports produced by the center were of international standards. There were lacunae in "patient disposition" in few of the reports. 2010 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69014964005 en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.3 Vol.8 |
| format | Artículo científico |
| id | redalyc_69014964005 |
| institution | Redalyc |
| language | en |
| publishDate | 2010 |
| publisher | Centro de investigaciones y Publicaciones Farmacéuticas |
| spellingShingle | Pattern and quality of scientific communications on drug safety produced by a regional pharmacovigilance center in Nepal Subish PALAIAN Medicina Nepal Periodicals as Topic Adverse Drug Reaction Reporting Systems Pattern and quality of scientific communications on drug safety produced by a regional pharmacovigilance center in Nepal Subish PALAIAN Mohamed I. M. IBRAHIM Pranaya MISHRA Medicina Nepal Periodicals as Topic Adverse Drug Reaction Reporting Systems Analyzing the pattern and quality of scientific communications on pharmacovigilance can help the regional centers in Nepal and other developing countries to develop approaches for communicating effectively medicine safety issues. This kind of research is lacking in developing countries. Objectives: To analyze the pattern and quality of scientific communications on drug safety produced by the regional pharmacovigilance center at western Nepal. Methodology: Various conference abstracts and journal publications produced by the center during its initial four years of establishment (14th September 2004 till 13th September 2008) were identified. These communications were categorized in to case reports, review articles, conference presentations, short communications, newsletter and bulletin articles, original research and case series. In addition, the quality of the case reports were evaluated as per International Society of Pharmacovigilance/International Society of Pharmacoepidemiology (ISoP/ISPE) guidelines on the requirements for submitting case reports on adverse event reports in biomedical journals.Results: During the study period, 53 scientific communications were produced by the staff of the regional pharmacovigilance center in relation with drug safety. Among these, 18 (34%) were related to case reports and letters. The median (interquartile range) age of the patients described in the case reports was 46.5 (21.7-51.2) years. Among the total 18 ADRs, four were fixed drug eruptions, followed by contact dermatitis (n=2). Majority of the published case reports were related to skin (n=13; 72.2%). Antimicrobials were responsible for 27.8% (n=5) of the case reports. Among the 18 case reports published by the pharmacovigilance center, a majority followed the ISoP/ISPE guidelines. Few parameters like physical examination of the patient experiencing ADR, patient disposition, dosage and administration of the suspected drugs, and drugreaction interface were missing in few of the cases. Conclusion: A high percentage of the scientific communications were "case reports". A high proportion of the case reports produced by the center were of international standards. There were lacunae in "patient disposition" in few of the reports. 2010 artículo científico 1885-642X https://www.redalyc.org/articulo.oa?id=69014964005 en http://www.redalyc.org/revista.oa?id=690 Pharmacy Practice application/pdf Centro de investigaciones y Publicaciones Farmacéuticas Pharmacy Practice (España) Num.3 Vol.8 |
| title | Pattern and quality of scientific communications on drug safety produced by a regional pharmacovigilance center in Nepal |
| topic | Medicina Nepal Periodicals as Topic Adverse Drug Reaction Reporting Systems |
| url | https://www.redalyc.org/articulo.oa?id=69014964005 |